| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Evaluation of Estrogen Dependency of Human Breast Cancers : I. Cytochemical study of estrogen receptor m human breast cancer tissue |
|
言語 |
en |
| タイトル |
|
|
タイトル |
ヒト乳癌におけるエストローゲン依存性の検討 : I. ヒト乳癌組織におけるエストローゲンレセプターの細胞化学的研究 |
|
言語 |
ja |
| 作成者 |
Nishiki, Masayuki
Yamane, Motoi
Amano, Kuniki
Yasuda, Katsuki
Okumichi, Tsuneo
Ezaki, Haruo
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Estrogen receptor |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Cytochemical study |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Breast cancer |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Fluorescent estradiol conjugate |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
We have had an opportunity to determine estrogen receptor (ER) in cytoplasmic fractions of primary breast cancer specimens taken from 79 patients under a fluorescent microscope using fluorescent estradiol conjugate as a tracer. In this study, an estrogen receptor is reported as positive when not less than 10% of carcinoma cells incorporate fluorescent estradiol conjugate into cytoplasma. The ER positive rate was 61% in the total cases, varying by age: 70% in 40s and younger, 43% in 50s, and 60% in 60s and older patients. Sixty-eight % of premenopausal breast cancers conpared to 54% of postmenopausal ones were ER positive. Broken down by the histological type, the rates were 70% in papilla-tubular carinoma, 59 % in medullary tubular carcinoma, and 57 % in scirrhous type. The rates by tumor size according to the clinical TNM classification were 70 % in T1, 59% in T2, 91% in T3, and 34% in T4. The rates by stage difined by the pathological TNM classification were 65 % in Stage I, 50% in Stage II, 87% in Stage III, and 45% in Stage IV. We discuss our findings and review others, as well. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6090348 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
157 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 33,
号 2,
p. 157-161,
発行日 1984-06
|
| 旧ID |
38196 |
HiroshimaJMedSci_33_157.pdf (592.6 KB)
