{"created":"2025-02-23T06:18:43.225704+00:00","id":2012931,"links":{},"metadata":{"_buckets":{"deposit":"80431b90-eb7c-4466-8114-5fd3cfa87798"},"_deposit":{"created_by":41,"id":"2012931","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2012931"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02012931","sets":["1727147343679:1730442224523:1730442339632"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Evaluation of Estrogen Dependency of Human Breast Cancers : I. Cytochemical study of estrogen receptor m human breast cancer tissue","subitem_title_language":"en"},{"subitem_title":"ヒト乳癌におけるエストローゲン依存性の検討 : I. ヒト乳癌組織におけるエストローゲンレセプターの細胞化学的研究","subitem_title_language":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nishiki, Masayuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Nishiki","familyNameLang":"en"}],"givenNames":[{"givenName":"Masayuki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yamane, Motoi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Yamane","familyNameLang":"en"}],"givenNames":[{"givenName":"Motoi","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Amano, Kuniki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Amano","familyNameLang":"en"}],"givenNames":[{"givenName":"Kuniki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yasuda, Katsuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Yasuda","familyNameLang":"en"}],"givenNames":[{"givenName":"Katsuki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Okumichi, Tsuneo","creatorNameLang":"en"}],"familyNames":[{"familyName":"Okumichi","familyNameLang":"en"}],"givenNames":[{"givenName":"Tsuneo","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ezaki, Haruo","creatorNameLang":"en"}],"familyNames":[{"familyName":"Ezaki","familyNameLang":"en"}],"givenNames":[{"givenName":"Haruo","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Estrogen receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"Cytochemical study","subitem_subject_scheme":"Other"},{"subitem_subject":"Breast cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Fluorescent estradiol conjugate","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"We have had an opportunity to determine estrogen receptor (ER) in cytoplasmic fractions of primary breast cancer specimens taken from 79 patients under a fluorescent microscope using fluorescent estradiol conjugate as a tracer. In this study, an estrogen receptor is reported as positive when not less than 10% of carcinoma cells incorporate fluorescent estradiol conjugate into cytoplasma.    The ER positive rate was 61% in the total cases, varying by age: 70% in 40s and younger, 43% in 50s, and 60% in 60s and older patients.    Sixty-eight % of premenopausal breast cancers conpared to 54% of postmenopausal ones were ER positive.    Broken down by the histological type, the rates were 70% in papilla-tubular carinoma, 59 % in medullary tubular carcinoma, and 57 % in scirrhous type.    The rates by tumor size according to the clinical TNM classification were 70 % in T1, 59% in T2, 91% in T3, and 34% in T4.    The rates by stage difined by the pathological TNM classification were 65 % in Stage I, 50% in Stage II, 87% in Stage III, and 45% in Stage IV.    We discuss our findings and review others, as well.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University School of Medicine"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"157"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1984-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"161","bibliographicPageStart":"157","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"6090348","subitem_relation_type_select":"PMID"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_33_157.pdf","filesize":[{"value":"592.6 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2012931/files/HiroshimaJMedSci_33_157.pdf"},"version_id":"2c307cb5-2bc2-47e8-86f7-abed6a4fdd37"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"38196"},"item_title":"Evaluation of Estrogen Dependency of Human Breast Cancers : I. Cytochemical study of estrogen receptor m human breast cancer tissue","item_type_id":"40003","owner":"41","path":["1730442339632"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2012931","relation_version_is_last":true,"title":["Evaluation of Estrogen Dependency of Human Breast Cancers : I. Cytochemical study of estrogen receptor m human breast cancer tissue"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T02:53:18.701756+00:00"}