WEKO3
アイテム
白血病細胞の α-マンノシダーゼと β-ガラクトシダーゼのアイソザイムパターン
https://hiroshima.repo.nii.ac.jp/records/2012865
https://hiroshima.repo.nii.ac.jp/records/2012865f47ec61a-dc29-4682-b9f8-1b45ebb7e82f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_32_207.pdf (411.1 KB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Isoenzyme Profiles of α-Mannosidase and β-Galactosidase in Leukemic Cells | |||||||||||
| 言語 | en | |||||||||||
| タイトル | ||||||||||||
| タイトル | 白血病細胞の α-マンノシダーゼと β-ガラクトシダーゼのアイソザイムパターン | |||||||||||
| 言語 | ja | |||||||||||
| 作成者 |
Tanaka, Takeo
× Tanaka, Takeo
× Kobayashi, Masao
× Usui, Tomofusa
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| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Isoenzyme Profiles | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | α-mannosidase | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | β-galactosidase | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Leukemia | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | NDC | |||||||||||
| 主題 | 490 | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述 | The isoenzyme profiles of α-mannosidase and β-galactosidase in leukemic cells were examined with DEAE-Sephadex chromatography. A clear difference of these constituent isoenzymes was found between normal lymphocytes and granulocytes. In leukemic cells, the components of a-mannosidase eluting early (fraction I to III) from the chromatography were specific for myelogenous leukemia. No case of acute non-T/ non-B lymphocytic leukemia (ALL) or T-cell leukemia demonstrated these components. Leukemic cells except for T-cell leukemia also demonstrated significant increase of an α-mannosidase component which eluted with 0.2 M of KCl (fraction VI). There was no type specific alteration of β-galactosidase isoenzymes among examined leukemias. ALL and T-cell leukemia had isoenzymes of β-galactosidase similar to those of normal lymphocytes. However, an increase of an β-galactosidase component eluted with 0.3M of KCl (fraction VII) was found in acute myelocytic leukemia and chronic myelo (mono) cytic leukemia. These enzyme analysis may be useful for investigating intrinsic abnormalities in leukemic cells. | |||||||||||
| 言語 | en | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | This work was supported in part by Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan. | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Hiroshima University School of Medicine | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 関連情報 | ||||||||||||
| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | 6413460 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0018-2052 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00664312 | |||||||||||
| 開始ページ | ||||||||||||
| 開始ページ | 207 | |||||||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 32, 号 2, p. 207-212, 発行日 1983-06 |
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| 旧ID | 38341 | |||||||||||
