| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Titanium Immobilized with an Antimicrobial Peptide Derived from Histatin Accelerates the Differentiation of Osteoblastic Cell Line, MC3T3-E1 |
|
言語 |
en |
| 作成者 |
Makihira, Seicho
Shuto, Takahiro
Nikawa, Hiroki
Okamoto, Keishi
Mine, Yuichi
Takamoto, Yuko
Ohara, Masaru
Tsuji, Koichiro
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
antimicrobial peptide |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
titanium surface |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
MC3T3-E1 cells |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
The objective of this study was to evaluate the effect of titanium immobilized with a cationic antimicrobial peptide (JH8194) derived from histatin on the biofilm formation of Porphyromonas gingivalis and differentiation of osteoblastic cells (MC3T3-E1). The titanium specimens (Ti) were immobilized with JH8194, according to the method previously described. The colonization of P. gingivalis on JH8194-Ti was significantly lower than that on control- and blocking-Ti. JH8194-Ti enhanced the mRNA expressions of Runx2 and OPN, and ALPase activity in the MC3T3-E1, as compared with those of control- and blocking-Ti. These results, taken together, suggested the possibility that JH8194-Ti may be a potential aid to shorten the period of acquiring osseointegration. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Molecular Diversity Preservation International-MDPI |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.3390/ijms11041458 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.3390/ijms11041458 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1422-0067 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12038549 |
| 開始ページ |
|
|
開始ページ |
1458 |
| 書誌情報 |
International Journal of Molecular Sciences
International Journal of Molecular Sciences
巻 11,
号 4,
p. 1458-1470,
発行日 2010-04-02
|
| 旧ID |
30399 |
IntJMolSci_11_1458.pdf (379.9 KB)
