| Item type |
デフォルト(1) |
| 公開日 |
2025-07-16 |
| タイトル |
|
|
タイトル |
A liquid crystal world for the origins of life |
|
言語 |
en |
| 作成者 |
Jia, Tony Z.
Bellini, Tommaso
Clark, Noel
Fraccia, Tommaso P.
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is the accepted version of the following article, accepted for publication in Emerging Topics in Life Sciences: [Tony Z. Jia; Tommaso Bellini; Noel Clark; Tommaso P. Fraccia ], “[A liquid crystal world for the origins of life］” Emerging Topics in Life Sciences, [2022], [Vol･6-6], [557-569]. Please note: This is not the final Version of Record (VoR). The final published version is available from the journal’s website: https://doi.org/10.1042/ETLS20220081 The Version of Record is published by Portland Press on behalf of the Biochemical Society and the Royal Society of Biology. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is not the published version. Please cite only the published version. |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
chemical evolution |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
liquid crystals |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nucleic acids |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
origins of life |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
self-assembly |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Nucleic acids (NAs) in modern biology accomplish a variety of tasks, and the emergence of primitive nucleic acids is broadly recognized as a crucial step for the emergence of life. While modern NAs have been optimized by evolution to accomplish various biological functions, such as catalysis or transmission of genetic information, primitive NAs could have emerged and been selected based on more rudimental chemical–physical properties, such as their propensity to self-assemble into supramolecular structures. One such supramolecular structure available to primitive NAs are liquid crystal (LC) phases, which are the outcome of the collective behavior of short DNA or RNA oligomers or monomers that self-assemble into linear aggregates by combinations of pairing and stacking. Formation of NA LCs could have provided many essential advantages for a primitive evolving system, including the selection of potential genetic polymers based on structure, protection by compartmentalization, elongation, and recombination by enhanced abiotic ligation. Here, we review recent studies on NA LC assembly, structure, and functions with potential prebiotic relevance. Finally, we discuss environmental or geological conditions on early Earth that could have promoted (or inhibited) primitive NA LC formation and highlight future investigation axes essential to further understanding of how LCs could have contributed to the emergence of life. |
|
言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Collaborative work between T.Z.J. and T.P.F. was funded by the Programme Exploration France, sponsored by the Embassy of France in Japan. T.Z.J. is further supported by JSPS Grant-in-aid 21K14746, a Start-up Grant from the Earth-Life Science Institute (ELSI), and by the Assistant Staffing Program by the Gender Equality Section, Diversity Promotion Office, Tokyo Institute of Technology. T.Z.J. is a member of ELSI of the Tokyo Institute of Technology, which is sponsored by a grant from the Japan Ministry of Education, Culture, Sports, Science and Technology as part of the World Premier International Research Center Initiative. N.C. is funded by U.S. National Science Grant DMR 2005212. T.P.F. is further supported by a Junior Research Chair fellowship from IPGG (Laboratoire d’Excellence, ‘Investissement d’avenir’ program ANR-10-IDEX-0001-02 PSL and ANR-10-LABX-31), ANR-10-EQPX-34 and IPGG AAP High Risk2020 grant |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Portland Press |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1042/ETLS20220081 |
| 助成情報 |
|
|
|
助成機関識別子タイプ |
Crossref Funder |
|
|
助成機関識別子タイプURI |
https://doi.org/10.13039/501100001691 |
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|
助成機関名 |
日本学術振興会 |
|
|
言語 |
ja |
|
|
助成機関名 |
Japan Society for the Promotion of Science |
|
|
言語 |
en |
|
|
研究課題番号URI |
https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21K14746/ |
|
|
研究課題番号 |
21K14746 |
|
|
研究課題名 |
Biomolecule compartmentalization by phase separated protocells |
|
|
言語 |
en |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2397-8554 |
| 書誌情報 |
en : Emerging Topics in Life Sciences
巻 6,
号 6,
p. 557-569,
発行日 2022-11-14
|
ETLS_6-6_557.pdf (1.9 MB)
