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Effect of haemodiafiltration versus haemodialysis on vascular access patency when starting haemodialysis
https://hiroshima.repo.nii.ac.jp/records/2040743
https://hiroshima.repo.nii.ac.jp/records/2040743eff11052-d59e-46a4-9919-d45dd01d874b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
NDT_gfaf017.pdf (1.7 MB)
Download is available from 2026/1/24.
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| Item type | デフォルト(1) | |||||||||||||||||||
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| 公開日 | 2025-06-17 | |||||||||||||||||||
| タイトル | ||||||||||||||||||||
| タイトル | Effect of haemodiafiltration versus haemodialysis on vascular access patency when starting haemodialysis | |||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 作成者 |
Yoshida, Mahoko
× Yoshida, Mahoko
× Maeoka, Yujiro
× Takahashi, Akira
× Ishiuchi, Naoki
× Osaki, Yosuke
× Sasaki, Kensuke
× Masaki, Takao
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| アクセス権 | ||||||||||||||||||||
| アクセス権 | embargoed access | |||||||||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_f1cf | |||||||||||||||||||
| 権利情報 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 権利情報 | This is a pre-copyedited, author-produced version of an article accepted for publication in Nephrology Dialysis Transplantation following peer review. The version of record Mahoko Yoshida, Yujiro Maeoka, Akira Takahashi, Naoki Ishiuchi, Yosuke Osaki, Kensuke Sasaki, Takao Masaki,Effect of haemodiafiltration versus haemodialysis on vascular access patency when starting haemodialysis, Nephrology Dialysis Transplantation, 2025, gfaf017, is available online at:https://doi.org/10.1093/ndt/gfaf017. | |||||||||||||||||||
| 権利情報 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 権利情報 | This is not the published version. Please cite only the published version. | |||||||||||||||||||
| 権利情報 | ||||||||||||||||||||
| 言語 | ja | |||||||||||||||||||
| 権利情報 | この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | haemodiafiltration | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | haemodialysis | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | patency rate | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | vascular access | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | vascular access interventional therapy | |||||||||||||||||||
| 内容記述 | ||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||
| 内容記述 | Background Haemodiafiltration (HDF) therapy improves the prognosis by reducing inflammation and oxidative stress and improving endothelial function. These factors contribute to vascular access (VA) stenosis, one of the most common complications in patients on haemodialysis (HD) or HDF. This study aimed to assess the efficacy of HDF on VA patency. Methods This multicentre, prospective, observational study with post hoc analysis included 612 patients among 643 who underwent VA procedures and started dialysis between April 2012 and March 2021. A total of 516 patients were on HD since starting dialysis, while 96 switched to HDF after starting dialysis. One-to-one propensity score matching was performed to compare the 24-month patency rates of VA between groups by Kaplan–Meier and logrank tests, and a Cox proportional hazards regression analysis was used to identify factors affecting patency rates. Results There were 87 patients in each group. The 24-month primary patency rates were 74.2% for HDF and 47.7% for HD (P < .001). A multivariate Cox proportional hazards analysis showed that a history of cardiovascular disease {hazard ratio [HR] 2.29 [95% confidence interval (CI) 1.21–4.34], P = .01} and higher haemoglobin A1c values [HR 1.37 (95% CI 1.00–1.82), P = .04] were associated with poor 24-month primary patency. However, HDF [HR 0.30 (95% CI 0.16–0.56), P < .001] and use of statins [HR 0.50 (95% CI 0.27–0.94), P = .03] were associated with better patency. A stratified analysis showed that HRs for loss of VA patency were lower in patients with HDF than in those with HD in the subgroups of ≥65 years, male sex, radiocephalic arteriovenous fistula, a history of diabetes mellitus or cardiovascular disease, haemoglobin concentrations <10 g/dl and albumin concentrations <3.5 g/dl. Conclusions HDF potentially improves VA patency rates compared with HD, even in patients with cardiovascular disease or diabetes, commonly associated with poor patency. |
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| 言語 | en | |||||||||||||||||||
| 出版者 | ||||||||||||||||||||
| 出版者 | Oxford University Press | |||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 日付 | ||||||||||||||||||||
| 日付 | 2026-01-24 | |||||||||||||||||||
| 日付タイプ | Available | |||||||||||||||||||
| 言語 | ||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||
| 出版タイプ | AM | |||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||||||
| 関連情報 | ||||||||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||
| 関連識別子 | https://doi.org/10.1093/ndt/gfaf017 | |||||||||||||||||||
| 書誌情報 |
en : Nephrology Dialysis Transplantation p. gfaf017, 発行日 2025-01-24 |
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| 備考 | ||||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 値 | The full-text file will be made open to the public on 24 January 2026 in accordance with publisher's 'Terms and Conditions for Self-Archiving' | |||||||||||||||||||
