Item type |
デフォルト(1) |
公開日 |
2025-06-11 |
タイトル |
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タイトル |
General anesthesia with remimazolam for tooth extraction in a patient with Noonan syndrome and hypertrophic obstructive cardiomyopathy: A case report |
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言語 |
en |
作成者 |
Kamio, Hisanobu
Oue, Kana
Asada , Yasuyuki
Ito, Nanako
Imamura, Serika
Doi, Mitsuru
Shimizu, Yoshitaka
Yoshida, Mitsuhiro
Yanamoto, Souichi
Hanamoto, Hiroshi
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
en |
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権利情報 |
©[ 2024]. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/ |
権利情報 |
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言語 |
en |
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権利情報 |
This is not the published version. Please cite only the published version. |
権利情報 |
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言語 |
ja |
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権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Noonan syndrome |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Hypertrophic cardiomyopathy |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Hypertrophic obstructive cardiomyopathy |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Remimazolam |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Noncardiac surgery |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Noonan syndrome (NS) is characterized by various abnormalities and is complicated with cardiac diseases, such as hypertrophic cardiomyopathy, in > 80% of cases. Minimum hemodynamic changes are a crucial factor during general anesthesia in such patients. We report the case of a patient with NS and hypertrophic obstructive cardiomyopathy (HOCM) who underwent general anesthesia using remimazolam, a new ultrashort-acting benzodiazepine anesthetic, which is expected to cause less circulatory depression. A 19-year-old woman with NS complicated with HOCM was scheduled to undergo extraction of the wisdom teeth and second molar under general anesthesia. Preoperative evaluation revealed HOCM with left ventricular outflow tract obstruction and the patient had chronic heart failure. After the placement of an arterial line under moderate sedation with remimazolam, general anesthesia was induced with remimazolam, fentanyl, and rocuronium, followed by anesthesia maintenance with remimazolam and remifentanil. Tracheal intubation was performed using videolaryngoscopy. Local anesthesia and inferior alveolar nerve block were performed using adrenaline-free local anesthetics. Intraoperatively, low-dose phenylephrine was administered continuously to maintain peripheral vascular resistance. At the end of surgery, the endotracheal tube was replaced with an i-gel® supraglottic airway device before emergence from general anesthesia. After full recovery from anesthesia, the i-gel® was removed, and the patient was transferred to the hospital ward. The perioperative blood pressure and heart rate were maintained within normal ranges, and no cardiovascular events occurred during anesthesia. Anesthesia management using remimazolam and low-dose phenylephrine with reduction in perioperative stress may provide an appropriate circulatory condition for noncardiac surgery in patients with HOCM. |
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言語 |
en |
出版者 |
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出版者 |
Elsevier |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.ajoms.2024.04.016 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2212-5558 |
書誌情報 |
en : JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
巻 37,
号 1,
p. 108-111,
発行日 2024-05-02
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