| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
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|
タイトル |
Frequencies of Dicentric Chromosome and Translocation in Lymphocytes from Residents in Radio-contaminated Villages near Semipalatinsk Nuclear Explosion Test Site |
|
言語 |
en |
| 作成者 |
Tanaka, Kimio
Iida, Shozho
Takeichi, Nobuo
Hoshi, Masaharu
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2012 Institute for Peace Science, Hiroshima University |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
319 |
| 内容記述 |
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|
内容記述 |
More than 400 above-ground and underground nuclear explosion tests were conducted at Semipalatinsk nuclear explosion test site (SNETS). The significant radioactive substances was released and radioactive plumes moved on villages at the time of explosion test, then residents in villages near SNETS are considered to be exposed internally and externally. In order to assess the biological effects on residents, frequencies of chromosome aberrations in peripheral blood lymphocytes were observed in 116 residents living in 3 villages near SNETS and 46 residents in a non-contaminated village by conventional Giemsa staining method and fluorescent in situ hybridization (FISH). Frequencies of dicentric and ring chromosomes in residents from the 3 villages were 1.5-2.55 per 1,000 cells, comparing to 0.78 in control area. Residents in contaminated areas had more complex chromosome aberrations. Frequencies of stable-type chromosome aberrations such as translocation were detected in 0.1% and 0.07% in 2 contaminated villages, while 0.02% in control area. More sensitive FISH analysis of chromosome subset revealed higher frequency of translocation (2.17%) in a resident. Multiple chromosome aberrations (MCA) involving more than 10 abnormal chromosomes were found in 0.12-0.42 % of observed cells among all villages, irrespective of radio-contamination. These results indicate that residents living adjacent SNETS were exposed internally and externally, but their estimated external doses were less than previously estimated 140-440 mGy, though how internal exposure was contributed to the higher incidence of chromosome aberrations is unclear. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
広島大学平和科学研究センター |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
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|
ID登録 |
10.15027/33649 |
|
ID登録タイプ |
JaLC |
| 収録物識別子 |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10456537 |
| 開始ページ |
|
|
開始ページ |
215 |
| 書誌情報 |
IPSHU English Research Report Series
IPSHU English Research Report Series
号 28,
p. 215-223,
発行日 2012-03
|
| 旧ID |
33649 |
ipshu_en_28_215.pdf (9.1 MB)
