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  1. 広島大学の刊行物
  2. Hiroshima Journal of Medical Sciences
  3. 68巻1号

Symptomatic Developmental Venous Anomaly with an Increased β2-microglobulin Level in Cerebrospinal Fluid: A Case Report

https://hiroshima.repo.nii.ac.jp/records/2013789
https://hiroshima.repo.nii.ac.jp/records/2013789
0237394c-48bd-4461-ba58-7f81a5897f4e
名前 / ファイル ライセンス アクション
HiroshimaJMedSci_68_13.pdf HiroshimaJMedSci_68_13.pdf (1.5 MB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル Symptomatic Developmental Venous Anomaly with an Increased β2-microglobulin Level in Cerebrospinal Fluid: A Case Report
言語 en
作成者 Komasaku, Soichiro

× Komasaku, Soichiro

en Komasaku, Soichiro

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Hanaya, Ryosuke

× Hanaya, Ryosuke

en Hanaya, Ryosuke

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Yonenaga, Masanori

× Yonenaga, Masanori

en Yonenaga, Masanori

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Kubo, Fumikatsu

× Kubo, Fumikatsu

en Kubo, Fumikatsu

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Eiraku, Naoto

× Eiraku, Naoto

en Eiraku, Naoto

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Yamasaki, Fumiyuki

× Yamasaki, Fumiyuki

en Yamasaki, Fumiyuki

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Arita, Kazunori

× Arita, Kazunori

en Arita, Kazunori

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Yoshimoto, Koji

× Yoshimoto, Koji

en Yoshimoto, Koji

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
権利情報 Copyright (c) 2019 Hiroshima University Medical Press
主題
主題Scheme Other
主題 developmental venous anomaly
主題
主題Scheme Other
主題 venous infarction
主題
主題Scheme Other
主題 β2-microglobulin
内容記述
内容記述 Background: Gadolinium-enhanced magnetic resonance imaging (MRI) can be used to observe the progression of cerebral infarction, which sometimes mimics malignant brain tumors. While the β2-microglobulin (β2MG) level in blood plasma or cerebrospinal fluid (CSF) is useful for the diagnosis of malignant tumors or degenerative diseases, these results may create confusion regarding a definitive diagnosis, because it is not a specific marker. We present a rare case of symptomatic developmental venous anomaly (DVA), accompanied by transient, irregular, enhanced cerebral lesions and elevated β2MG in the CSF. Case Description: A 56-year-old woman developed dysarthria and underwent MRI, which revealed a right frontal hyperintense area around a previous lesion on diffusion-weighted imaging (DWI). She was treated based on the tentative diagnosis of an ischemic cerebrovascular event, and symptoms subsided in 3 days. MRI on day 7 revealed an enlargement of the hyperintense area on DWI. Post-gadolinium MRI showed multiple, enhanced patchy areas in the right frontal lobe and an abnormally large vein connected to dilated medullary venules, indicating DVA. Magnetic resonance angiography showed no stenosis or arterial occlusion. The β2MG level in the CSF was elevated at 2,061 μg/l, and a differential diagnosis from malignant tumor was required. However, MRI on day 23 revealed total disappearance of the enhanced lesions and a decrease in the high intensity area on DWI. Considering the clinical course, the DVA was symptomatic because of the perfusion disturbance. Conclusion: Careful evaluation is necessary when considering the associated pathologies and potential complications of DVA if detected near a gadolinium-enhanced lesion.
言語 en
出版者
出版者 Hiroshima University Medical Press
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
関連情報
識別子タイプ DOI
関連識別子 10.24811/hjms.68.1_13
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.24811/hjms.68.1_13
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0018-2052
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2433-7668
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA00664312
開始ページ
開始ページ 13
書誌情報 Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences

巻 68, 号 1, p. 13-18, 発行日 2019-03
旧ID 47739
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