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  1. 広島大学の刊行物
  2. Hiroshima Journal of Medical Sciences
  3. 67巻

Effect of Chronic Organophosphate Poisoning on Attention Deficit and Memory Impairment

https://hiroshima.repo.nii.ac.jp/records/2013776
https://hiroshima.repo.nii.ac.jp/records/2013776
5d623c9e-90e4-466d-9d82-cdae35451540
名前 / ファイル ライセンス アクション
HiroshimaJMedSci_67s_127.pdf HiroshimaJMedSci_67s_127.pdf (238.6 KB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル Effect of Chronic Organophosphate Poisoning on Attention Deficit and Memory Impairment
言語 en
作成者 Halim, Irene Andriani

× Halim, Irene Andriani

en Halim, Irene Andriani

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Erni

× Erni

en Erni

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Gumay, Ainun Rahmasari

× Gumay, Ainun Rahmasari

en Gumay, Ainun Rahmasari

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Bakri, Saekhol

× Bakri, Saekhol

en Bakri, Saekhol

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Maharani, Nani

× Maharani, Nani

en Maharani, Nani

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Muniroh, Muflihatul

× Muniroh, Muflihatul

en Muniroh, Muflihatul

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Bakhtiar, Yuriz

× Bakhtiar, Yuriz

en Bakhtiar, Yuriz

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Hardian

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en Hardian

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
権利情報 Copyright (c) 2018 Hiroshima University Medical Press
主題
主題Scheme Other
主題 Organophosphate pesticide
主題
主題Scheme Other
主題 chronic
主題
主題Scheme Other
主題 memory
主題
主題Scheme Other
主題 attention
主題
主題Scheme Other
主題 acetylcholinesterase
主題
主題Scheme NDC
主題 490
内容記述
内容記述 Introduction: Organophosphate pesticide poisoning is a common health problem in Indonesia. By inhibiting acetylcholinesterase mechanism, chronic organophosphate poisoning may lead some cognitive consequences included attention deficit and memory impairment. This study investigates the effect of chronic organophosphate exposure in attention deficit and memory impairment. Method: A cross-sectional study was conducted in 2 different groups, each consisting of 33 male farmers in Banjarnegara, aged 18-59 years old who are occupationally exposed to organophosphate pesticide for at least 2 years. First group was carried on memory examination using memory impairment screen (MIS) instrument while in second group, attention examination was measured by attention network test (ANT). Vein blood samples analyzed semiquantitatively using Tintometer to know the level of blood acetylcholinesterase (AChE) activity. Data were analyzed using Chi square and Spearman. Result: In the first group, 15 (45.5%) samples were found mildly poisioned, while 18 (54.5%) samples were found normal. Among 33 samples, 11 (33.3%) samples have memory impairment. Overall, memory impairment prevalence was higher in sample with mild poisoning, with prevalence ratio of 1,78 (p=0.026). In second group, 54.5% (n=18) farmers were found mildly poisioned while 45.5% (n=15) others had normal AChE activity. Lower AChE activity were significantly correlated with poorer performance in total attention score (r = -0.539; p< 0.00), especially alerting (r= -0.653; p< 0.00) and orienting function (r = -0.632; p< 0.00). Conclusion. Chronic organophosphate poisioning seems to have deleterious effects on memory and attention.
言語 en
出版者
出版者 Hiroshima University Medical Press
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0018-2052
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA00664312
開始ページ
開始ページ 127
書誌情報 Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences

巻 67, p. 127-132, 発行日 2018-05
旧ID 45855
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