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The Effect of Stress on IL-17 Levels in an OVA-immunized Mice Allergic Model
https://hiroshima.repo.nii.ac.jp/records/2013773
https://hiroshima.repo.nii.ac.jp/records/201377311796db5-4f4f-4d35-93d2-9e11e6185ded
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_67s_110.pdf (195.6 KB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||||
| タイトル | ||||||||||||
| タイトル | The Effect of Stress on IL-17 Levels in an OVA-immunized Mice Allergic Model | |||||||||||
| 言語 | en | |||||||||||
| 作成者 |
Santosa, Yanuar Iman
× Santosa, Yanuar Iman
× Suprihati
× Dharmana, Edi
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| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 権利情報 | ||||||||||||
| 権利情報 | Copyright (c) 2018 Hiroshima University Medical Press | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Allergic Rhinitis | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Ovalbumin | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Stress | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Cortisol | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | IL-17 | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | NDC | |||||||||||
| 主題 | 490 | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述 | Objective: Evaluate the effect of stress on eosinophil count, levels of cortisol and levels of IL-17 in an OVA-immunized Mice Allergic model. Method: Eight teen female BALB/c mice divided into 3 groups. Negative control in group 1, Allergy control in group 2 group received ovalbumin sensitization only and stress treatment in Group 3 received ovalbumin sensitization and stress using water-immersion stress test on day 24th, 26th and 30th. All mice are terminated on 31st day, lungs and blood sample are collected and measured for eosinophil count microscopically, level of cortisol and level of IL-17 using ELISA. Results: Mean eosinophil count for group 1 is 0.48 per high power field (hpf), group 2 is 2,13 hpf, group 3 0.8 hpf. Mean cortisol level for group 1 is 9.13 ng/mL, group 2 is 10.85 ng/mL, group 3 25.47 ng/mL. Mean IL-17 level for group 1 66.71 pg/mL, group 2 is 22.36 pg/mL, group 3 is 26.38 pg/mL. Conclusion: The number of eosinophils in the allergy control in group 2 (2.13/hpf) was significantly higher than the negative control in group 1 (0.48/hpf) (p = 0.004). Levels of cortisol in the stress treatment in group 3 (25.47 ng/mL) were not significantly different from the allergy control in group 2 (10.85 ng / mL) (p = 0.180). Levels of IL-17 in the stress treatment in group 3 (26.38 pg / mL) did not differ significantly from the allergy control in group 2 (22.36) (p = 0.394). | |||||||||||
| 言語 | en | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Hiroshima University Medical Press | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0018-2052 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00664312 | |||||||||||
| 開始ページ | ||||||||||||
| 開始ページ | 110 | |||||||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 67, p. 110-115, 発行日 2018-05 |
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| 旧ID | 45852 | |||||||||||
