Item type |
デフォルトアイテムタイプ_(フル)(1) |
公開日 |
2023-03-18 |
タイトル |
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タイトル |
Propofol for Anesthesia and Postoperative Sedation Resulted in Fewer Inflammatory Responses than Sevoflurane Anesthesia and Midazolam Sedation after Thoracoabdominal Esophagectomy. |
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言語 |
en |
作成者 |
Nakanuno, Ryuichi
Yasuda, Toshimichi
Hamada, Hiroshi
Yoshikawa, Hiroshi
Nakamura, Ryuji
Saeki, Noboru
Kawamoto, Masashi
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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権利情報 |
Hiroshima University Medical Press |
主題 |
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主題Scheme |
Other |
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主題 |
Inflammatory response |
主題 |
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主題Scheme |
Other |
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主題 |
Propofol |
主題 |
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主題Scheme |
Other |
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主題 |
Sevoflurane |
主題 |
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主題Scheme |
Other |
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主題 |
Midazolam |
主題 |
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主題Scheme |
NDC |
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主題 |
490 |
内容記述 |
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内容記述 |
Responses to surgical stress can be modulated by anesthetics. We prospectively compared the effects of two different anesthetic/sedative techniques on the peak postoperative bladder temperature (BT) and the postoperative C-reactive protein (CRP) level. Twenty patients who were scheduled to undergo elective thoracoabdominal esophagectomy were allocated to receive either propofol anesthesia followed by propofol sedation (PP group, n = 10) or sevoflurane anesthesia followed by midazolam sedation (SM group, n = 10). In each case, the patient’s peak bladder temperature was measured on the morning after surgery, and their serum CRP levels were assessed on postoperative days (POD) 1, 2, and 3. The patients’ postoperative clinical courses were also evaluated. The peak postoperative BT (°C) (37.6 ± 0.4 vs. 38.2 ± 0.6, respectively; p <0.05) and the CRP level on POD 2 (mg/dl) (14.3 ± 3.9 vs. 20.6 ± 3.9, respectively; p <0.05) were lower in the PP group than in the SM group. The peak postoperative BT was positively correlated with the CRP level on POD 2 (R = 0.533, p < 0.05). There were no significant differences between the clinical course-related parameters in both groups. Proposal anesthesia and postoperative propofol sedation resulted in a reduced peak postoperative BT and lower CRP levels on POD 2 after esophagectomy than sevoflurane anesthesia followed by midazolam sedation. |
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言語 |
en |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
This study was supported by the Hiroshima University Support Foundation. |
出版者 |
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出版者 |
Hiroshima University Medical Press |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0018-2052 |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00664312 |
開始ページ |
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開始ページ |
31 |
書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 64,
号 3,
p. 31-37,
発行日 2015-09
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旧ID |
39059 |