| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Relationship between Intratumoral Hemorrhage and Overexpression of Vascular Endothelial Growth Factor (VEGF) in Pituitary Adenoma |
|
言語 |
en |
| 作成者 |
Arita, Kazunori
Kurisu, Kaoru
Tominaga, Atsushi
Sugiyama, Kazuhiko
Eguchi, Kuniki
Hama, Seiji
Yoshioka, Hiroyuki
Yamasaki, Fumiyuki
Kanou, Yukari
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Vascular endothelial growth factor |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Pituitary adenoma |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Hemorrhage |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
The authors investigated the relationship between hemorrhage and the expression of vascular endothelial growth factor (VEGF) in pituitary adenomas. The subjects were 39 patients with pituitary adenomas. Surgically obtained tumor tissue was immunohistochemically stained using antibodies against VEGF, CD-34, Ki-67, and anterior pituitary hormones. The expression of VEGF was graded as 0, 1+, and 2+. The relationship between intratumoral hemorrhage and factors such as tumor size, Ki-67 labeling indices, number of CD-34 positive vessels, and VEGF expression was examined by multivariate analysis. High-grade VEGF expression was the sole independent factor correlated with intratumoral hemorrhage. The number of CD-34 positive vessels had no effect on the incidence of hemorrhage in patients with pituitary adenomas. In conclusion, a positive relationship between VEGF expression and hemorrhage in pituitary adenoma was observed. The patho-mechanical significance of this correlation is under investigation. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
| 出版者 |
|
|
出版者 |
国立情報学研究所 |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
23 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 53,
号 2,
p. 23-27,
発行日 2004-06
|
| 旧ID |
17689 |
KJ00004268000.pdf (901.7 KB)
