| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Effect of the Angiotensin-converting Enzyme Inhibitor Enalapril on Post-transplant Erythrocytosis |
|
言語 |
en |
| 作成者 |
Marubayashi, Seiji
Yamamoto, Hiroyuki
Shibata, Satoshi
Fudaba, Yasuhiro
Miyata, Yoshihiro
Fukuma, Kazuyuki
Okada, Kazuro
Hinoi, Takao
Ikeda, Masahiro
Maeda, Takashi
Oshiro, Yoshio
Dohi, Kiyohiko
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Erythrocytosis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Renal transplantation |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Angiotensin converting enzyme inhibitor |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Post-transplant erythrocytosis (PTE) is increasingly recognized as a complication of kidney transplantation. In this study we report the effect of the angiotesin-converting enzyme (ACE) inhibitor enalapril on hematocrit (Ht) and erythropoietin in four patients with PTE. Four renal allograft recipients with Ht greater than 51 % were studied. Treatment was initiated with enalapril administered orally at a dose of 2.5 mg/day. All the patients had an increase of hemoglobin (Hb) (17.7 ± 0.64 g/dl), Ht (54.5 ± 1.29 %) and red blood cell count (REC) (584 ± 19.2 × 10⁴/μl). All patients responded to enalapril in 8 weeks with a significant decrease of Hb, Ht, and REC. In one patient, the downward trend was more rapid and sustained, and treatment had to be discontinued to prevent the development of anemia. Serum erythropoietin showed normal in all four patients and remained unchanged during the study, even after discontinuation of enalapril treatment. Serum creatinine remained relatively stable throughout the study. These results suggest that PTE may not be dependent upon circulating erythropoietin and that enalapril treatment may be an effective treatment of PTE without renal dysfunction. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
121 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 47,
号 3,
p. 121-124,
発行日 1998-09
|
| 旧ID |
37803 |
HiroshimaJMedSci_47_121.pdf (430.2 KB)
