| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Neutral Endopeptidase Activity in Serum and Cerebrospinal Fluid |
|
言語 |
en |
| 作成者 |
Muraki, Koutarou
Nakata, Yoshihiro
Simonaka, Hiroyuki
Inoue, Jun-ichi
Hirai, Yuko
Akiyama, Mitoshi
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Neutral endopeptidase |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Serum |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Cerebrospinal fluid |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Severe body pain |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
We measured neutral endopeptidase (NEP) activity in serum from non-smoking healthy Japanese and in cerebrospinal fluid (CSF) from patients without neurological or inflammatory diseases. The serum NEP activity (sNEP) of 25 males and 25 females, aged 20 to 65 years, ranged from 0.003 to 1.62 pmole/min/μl. There was no significant difference in sNEP activity between the sexes (male: 0.40 ± 0.34 pmole/min/μl vs female: 0.37 ± 0.30, mean ± S.D.). There was a significant positive correlation (p<0.05) between sNEP and age. The NEP activity in the CSF (cNEP) ranged from 0.07 to 0.63 pmole/min/μl. Male patients with benign prostate hypertrophy (BPH) showed cNEP activity of 0.21 ± 0.11 pmole/min/μl (n=13), and female patients with myoma uteri (MU) or dysplasia of the uterus mucosa (DUM) showed activity of 0.32 ± 0.20 (n=5). There was no significant difference in cNEP activity between the sexes. Three patients with severe body pain showed cNEP activity of 0.21, 0.15, and 0.16 pmole/min/μl, and these values were not dissimilar from those of the BPH, MU, or DUM patients. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
109 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 45,
号 4,
p. 109-112,
発行日 1996-12
|
| 旧ID |
37849 |
HiroshimaJMedSci_45_109.pdf (379.1 KB)
