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  1. 広島大学の刊行物
  2. Hiroshima Journal of Medical Sciences
  3. 43巻4号

Effectiveness of Assistance Circulations for Distal Circulatory Support during Cross-clamping of the Descending Thoracic Aorta

https://hiroshima.repo.nii.ac.jp/records/2013353
https://hiroshima.repo.nii.ac.jp/records/2013353
e0add0c5-241a-4560-99a4-d0910f2062f2
名前 / ファイル ライセンス アクション
HiroshimaJMedSci_43_135.pdf HiroshimaJMedSci_43_135.pdf (1.1 MB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル Effectiveness of Assistance Circulations for Distal Circulatory Support during Cross-clamping of the Descending Thoracic Aorta
言語 en
作成者 Liu, Gang

× Liu, Gang

en Liu, Gang

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
主題
主題Scheme Other
主題 Aorta
主題
主題Scheme Other
主題 Clamp
主題
主題Scheme Other
主題 Shunt
主題
主題Scheme NDC
主題 490
内容記述
内容記述 In order to find the ideal distal circulatory support during cross-clamping of the descending thoracic aorta, the author compared the effects of simple shunting (SS) and centrifugal pump (CP) on hemodynamics and metabolisms in mongrel dogs. In group I (control), the aorta was cross-clamped for two hours without SS or CP; in group II (SS), a temporary shunt was placed between the left common carotid and left femoral arteries during cross-clamping; in group III (CP), with left heart bypass, the flow was maintained about the same as that in group II; in group IV (CP), proximal pressure was maintained unchanged. Hemodynamic and metabolic parameters were recorded prior to cross-clamping and every 30 min for four hours during and after cross-clamping. All animals in group I suffered from hemodynamic instability, metabolic abnormalities and neurologic injury and died within 12 hours. Hemodynamic changes were more unstable in group III than in groups II and IV. Three dogs in group III and also in group IV but none in group II, suffered from neurologic injury. Metabolic changes in groups II, III and IV were not significant. The author conclude that hemodynamic and metabolic abnormalities can be minimized through the efficient use of a shunt in cross-clamping of the descending thoracic aorta and postoperative complications such as paraplegia, renal failure and hepatic dysfunction can be prevented. The centrifugal pump as a distal circulatory support device is able to maintain stable hemodynamics and normal distal organic metabolisms if aortic pressure proximal to the clamp is maintained essentially unchanged through regulation of pump flow. However, it is unable to prevent paraplegia during cross-clamping of the descending thoracic aorta for two hours. Shortening the time of cross-clamping of the descending thoracic aorta is necessary to prevent paraplegia.
言語 en
出版者
出版者 Hiroshima University Medical Press
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0018-2052
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA00664312
開始ページ
開始ページ 135
書誌情報 Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences

巻 43, 号 4, p. 135-144, 発行日 1994-12
旧ID 37892
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