| アイテムタイプ |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
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|
タイトル |
Effect of Androgen and Aging on Ornithine Decarboxylase Activity of Rat Ventral Prostate |
|
言語 |
en |
| 作成者 |
NAKAMOTO, Takahisa
OKADA, Mitsuo
NAKAMURA, Koji
NIHIRA, Hiromi
YASUKAWA, Akihiro
TAKENAKA, Ikumasa
NISHI, Nozomu
MATSUO, Yuhsi
WADA, Fumio
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| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
Ornithine decarboxylase activity |
| 主題 |
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主題Scheme |
Other |
|
主題 |
Aging |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Rat ventral prostate |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Tissue dihydrotestosterone content |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
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|
内容記述 |
The age-related alteration of androgen dependency in ornithine decarboxylase (ODC) activity was examined in ventral prostate from: (1) intact rats aged 6, 10, 50 and 100W; (2) castrated rats aged 10 and 100W; (3) 10 and 100W rats castrated for 7 days before injection with testosterone propionate for up to 7 days. Tissue dihydrotestosterone (DHT) contents in ventral prostate from intact rats aged 10 and 100W were also measured. ODC activity of rat ventral prostate declined with aging. Castration resulted in rapid decline in ODC activity of young mature rats (l0W) and the activity was restored to normal value by the injection of testosterone propionate. On the other hand, the changes in ODC activity of old rats (100W) induced by castration and androgen replacement were significantly slower than those of young mature rats. In young mature rats, ODC activity was apparently correlated with prostatic DHT contents. Although prostatic DHT contents of old rats retained a similar level to young mature rats, no such correlation between ODC activity and tissue DHT content was observed. These results showed androgen-sensitive nature of ODC activity. And the sensitivity might be affected by aging at a step by which androgen showed its action. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima Journal Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
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|
識別子タイプ |
PMID |
|
|
関連識別子 |
3654269 |
| 収録物識別子 |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
175 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 36,
号 2,
p. 175-178,
発行日 1987-06
|
| 旧ID |
49974 |
HiroshimaJMedSci_36_175.pdf (515.6 KB)
