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Effect of 1,2-Dimethylhydrazine and Hydrogen Peroxide for the Duodenal Tumorigenesis in Relation to Blood Catalase Activity in Mice
https://hiroshima.repo.nii.ac.jp/records/2013090
https://hiroshima.repo.nii.ac.jp/records/20130900a8fc551-950a-4cde-8cc9-ed89d48dddb4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_35_197.pdf (3.4 MB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Effect of 1,2-Dimethylhydrazine and Hydrogen Peroxide for the Duodenal Tumorigenesis in Relation to Blood Catalase Activity in Mice | |||||||||||||||
| 言語 | en | |||||||||||||||
| 作成者 |
ITO, Akihiro
× ITO, Akihiro
× WATANABE, Hiromitsu
× AOYAMA, Hideyuki
× NAKAGAWA, Yoshiyuki
× MORI, Masahiro
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| アクセス権 | ||||||||||||||||
| アクセス権 | open access | |||||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||||
| 主題 | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Duodenal tumor | |||||||||||||||
| 主題 | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Hydrogen peroxide | |||||||||||||||
| 主題 | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | 1,2-dimethylhydrazine | |||||||||||||||
| 主題 | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Catalase | |||||||||||||||
| 主題 | ||||||||||||||||
| 主題Scheme | NDC | |||||||||||||||
| 主題 | 490 | |||||||||||||||
| 内容記述 | ||||||||||||||||
| 内容記述 | Three different mouse strains, C3H/C^b_s C3H/HeN and B6C3 (C57BL x C3H) F1, having low, high and moderate catalase activities, were studied for duodenal tumorigenesis by the combined treatment with 1,2-dimethylhydrazine (DMH)* and hydrogen peroxide (HPO). DMH alone rarely induced duodenal tumors. Administration of HPO into 3 different mouse strains induced different frequencies of duodenal tumors ; 91.7% in C3H/C^b_s 9.5% in C3H/HeN and 31.8% in B6C3F1 mice. The incidence of duodenal tumors was significantly increased to 52.6% and 93.8% both in C3H/HeN and B6C3F1 mice by the combined administration of DMH and HPO. These increases in duodenal tumor were inversely correlated with the finding that administration of DMH or HPO alone or combined treatment of DMH and HPO significantly decreased mean blood catalase activities both in C3H and B6C3F1 mice. | |||||||||||||||
| 言語 | en | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | Hiroshima University School of Medicine | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
| 関連情報 | ||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||
| 関連識別子 | 3804779 | |||||||||||||||
| 収録物識別子 | ||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||
| 収録物識別子 | 0018-2052 | |||||||||||||||
| 収録物識別子 | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA00664312 | |||||||||||||||
| 開始ページ | ||||||||||||||||
| 開始ページ | 197 | |||||||||||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 35, 号 3, p. 197-200, 発行日 1986-09 |
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| 旧ID | 49921 | |||||||||||||||
