| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Nonspecific Mitogen Responses of Peripheral Lymphocytes in Levamisole-Treated Patients with Herpetic Stromal Keratitis |
|
言語 |
en |
| タイトル |
|
|
タイトル |
実質型角膜ヘルペス患者の mitogen response について |
|
言語 |
ja |
| 作成者 |
Sakata, Hiroshi
Hiyama, Noboru
Kondo, Hideaki
Hirakawa, Yuji
Yoshida, Hideto
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Herpetic stromal keratitis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Levamisole |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Nonspecific mitogen response |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
For the purpose of determining the effect of levamisole on cell-mediated immunity of patients with herpetic stromal keratitis, the response of peripheral lymphocytes to three mitogens (PHA, Con A and PWM) was examined in a total of 19 cases of herpetic stromal keratitis (16 effective cases) including 12 patients undergoing levamisole administration. As controls, a similar study was made on 35 healthy individuals without any ocular disease and on 19 patients with herpetic stromal keratitis who underwent steroid therapy. The response of lymphocytes to the three types of mitogens in cases undergoing levamisole therapy did not show any significant difference from that of healthy individuals. The response of peripheral lymphocytes to PHA and Con A in cases more than 7 months after cessation d levamisole administration and in cases undergoing steroid therapy was significantly elevated when compared with that of healthy cases. These results suggest that levamisole posseses the action of modulating the function of chiefly T-cells among the lymphocytes, through which it is effective against herpetic stromal keratitis. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6534935 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
813 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 33,
号 4,
p. 813-817,
発行日 1984-12
|
| 旧ID |
38290 |
HiroshimaJMedSci_33_813.pdf (325.4 KB)
