| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Studies on Pathogenesis of Reflux Pancreatitis |
|
言語 |
en |
| タイトル |
|
|
タイトル |
逆流性膵炎の病因に関する研究 |
|
言語 |
ja |
| 作成者 |
Kanao, Motoo
Nishiki, Masayuki
Takasugi, Sumiyoshi
Kawanishi, Hideki
Ezaki, Haruo
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Trypsin |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Kallikrein |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Elastase |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Reflux pancreatitis |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
The behaviors of proteases were examined in the pancreatic juice pooled into a closed duodenal loop and it was confirmed that the activation of proteases occurred quickly after the operation. Three kinds of pancreatic proteases, trypsin, kallikrein and elastase were purified from the pancreatic juice by succesive isoelectric focusing, Soya-bean trypsin inhibitor-Sepharose 4B affinity and Sephadex G-100 column chromatographies. Apparent molecular weights of the purified trypsin, kallikrein and elastase were 26,000, 31,000 and 25,000, respectively. Their isoelectric points were 5.0, 5.0 and 8.0, and their specific activities were 490 TAMe units, 45 TAMe units and 0.47 elastinolytic units/mg protein, respectively. All of these proteases induced a reflux pancreatitis in mongrel dogs and the reflux pancreatitis by the infusion of trypsin was the severest. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6398812 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
731 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 33,
号 4,
p. 731-737,
発行日 1984-12
|
| 旧ID |
38276 |
HiroshimaJMedSci_33_731.pdf (776.9 KB)
