| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Function of Trace Metal in Experimental Fulminant Hepatic Failure : Special Reference to Variation in Zinc Content in Liver |
|
言語 |
en |
| タイトル |
|
|
タイトル |
実験的急性肝不全における重金属動態 : 肝組織亜鉛量の変動を中心に |
|
言語 |
ja |
| 作成者 |
Kawanishi, Hideki
Nishiki, Masayuki
Tsuchiya, Taro
Ezaki, Haruo
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Hepatic failure |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Trace metal |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Zinc |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
D-galactosamine |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Hepatic ischemia |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
The authors prepared D-galactosamine (Gal) hepatic failure rats and hepatic failure dogs induced by hepatic ischemia and studied the correlation between the progress of hepatic failure and amount of trace metal in liver measured of the rats and dogs. After Gal was given, the rats rapidly fell into hepatic failure condition. They were sacrificed with the lapse of time and their zinc (Zn) content in liver was measured, which showed a decrease in relation to hepatic injury reaching a minimum of 67. 2 ± 3. 8 μg/g dry weight (that of control group: 149. 1 ± 23. 4, p<0. 05) 48 hr later. The hepatic failure dogs induced by hepatic ischemia also fell into hepatic failure after hepatic ischemia and died 17.5-112 hr (average 57.1 ± 38. 2) later. Positive correlation between the Zn. content in liver immediately after death and the survival time (r= 0. 653, p<0. 01). As a result, it is suggested that the Zn content in liver can be used as an index to the degree of hepatocyte injury and prognosis of hepatic failure. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6480369 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
27 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 33,
号 1,
p. 27-33,
発行日 1984-03
|
| 旧ID |
38170 |
HiroshimaJMedSci_33_27.pdf (472.9 KB)
