| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Carbonic Anhydrase I and II Levels in Erythrocytes of Chronic Renal Disease Patients |
|
言語 |
en |
| タイトル |
|
|
タイトル |
慢性腎疾患患者における赤血球炭酸脱水酵素レベル |
|
言語 |
ja |
| 作成者 |
Yamakido, Michio
Yorioka, Noriaki
Goriki, Kazuaki
Wada, Koji
Hata, Jyotaro
Nishimoto, Yukio
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Carbonic anhydrase |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Glomerulonephritis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Nephrotic syndrome |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Chronic hemodialysis |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Carbonic anhydrase isozymes, carbonic anhydrase I and II, also known as carbonate dehydratase, were isolated and purified from human erythrocytes. Rabbits were then immunized and the respective types of antisera were prepared. Using the antisera obtained, the carbonic anhydrase I and II levels in erythrocytes of healthy persons and patients with chronic glomerulonephritis, primary nephrotic syndrome, lupus nephritis and those undergoing chronic hemodialysis were determined by the single radial immunodiffusion method. Results showed that primary nephrotic syndrome, lupus nephritis and chronic hemodialysis patients had significantly higher carbonic anhydrase I levels than healthy persons, but an increase in carbonic anhydrase I level could not be demonstrated in patients with chronic glomerulonephritis. The carbonic anhydrase II level in chronic glomerulonephritis, primary nephrotic syndrome, lupus nephritis and chronic hemodialysis patients was significantly higher than that of healthy persons. Further, in the patients with chronic glomerulonephritis, a significant positive correlation was observed between carbonic anhydrase I and BUN, serum creatinine and total cholesterol levels, while there was a negative correlation between the PSP 15-minute value. Also a significant positive correlation was found between carbonic anhydrase II and total cholesterol levels. It is concluded that the determination of carbonic anhydrase I and II levels in human erythrocytes are important for the follow-up and evaluation of prognosis in chronic renal disease patients. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6807940 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
1 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 31,
号 1,
p. 1-6,
発行日 1982-03-10
|
| 旧ID |
38390 |
HiroshimaJMedSci_31_1.pdf (420.0 KB)
