| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
THE EFFECT OF EXPERIMENTAL HEMORRHAGIC SHOCK ON SERUM HDL-LEVEL IN RABBITS |
|
言語 |
en |
| タイトル |
|
|
タイトル |
家兎における血清 HDL におよぼす出血性ショックの影響 |
|
言語 |
ja |
| 作成者 |
Kajiyama, Goro
Takata, Koki
Matsuura, Hideo
Miyoshi, Akima
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
In order to study the changes in the levels of serum HDL (high density lipoprotein) by hypovolemic shock due to hemorrhage, blood was withdrawn from five female rabbits through a catheter inserted into an aortic arch via carotid artery. Three to five milliliters of blood intermittently withdrawn, which accerelated the hemorrhagic shock condition, were served for the lipid and lipoprotein analysis. During the experimental period, the portal blood flow and mean blood pressure of aortic arch were measured and Indocyamine green test (Rl5) performed frequently in the animals. (1) The serum concentration of HDL-cholesterol and HDL-phospholipids (d.>1.063 which involves VHDL (very high density lipoprotein)-phospholipids) gradually decreased and the total and LDL (low density lipoprotein) + VLDL (very low density lipoprotein)-cholesterol and phospholipids showed slight decreases immediately after the commencement of experiment and kept almost constant thereafter. (2) The magnitude of decrease in lipids was higher in HDL2 than HDL3 fraction, and VHDL-phospholipids were not affected by hemorrhagic shock. (3) The lipid and protein compositcon of HDL2 revealed a significant decrease in percent cholesterol and phospholipids accompanied by a relative increase in percent protein and triglycerides, and that of HDL3 showed no change in the serum 270 minutes after shock. (4) Substantially high elevation of catecholamines, temporal increase in free fatty acid and slight increase in serum triglycerides were observed during the experimental period. The hemorrhagic shock seems to disturb the regulation of serum HDL levels and its constituents. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6765676 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
255 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 30,
号 4,
p. 255-261,
発行日 1981-12-10
|
| 旧ID |
38399 |
HiroshimaJMedSci_30_255.pdf (4.4 MB)
