WEKO3
アイテム
甲状腺ホルモンがラットヒラメ筋における筋小胞体のCa^<2+>取り込みおよび収縮特性に及ぼす影響
https://hiroshima.repo.nii.ac.jp/records/2010338
https://hiroshima.repo.nii.ac.jp/records/20103385702ab69-b8c4-4208-ac17-86da51782bb3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
JpnJPhysFitnessSportsMed_53_509.pdf (656.6 KB)
|
| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | 甲状腺ホルモンがラットヒラメ筋における筋小胞体のCa^<2+>取り込みおよび収縮特性に及ぼす影響 | |||||||||||||
| 言語 | ja | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | EFFECTS OF THYROID HORMONE ON SARCOPLASMIC RETICULUM Ca^<2+> UPTAKE AND CONTRACTILE PROPERTIES IN RAT SOLEUS MUSCLE | |||||||||||||
| 言語 | en | |||||||||||||
| 作成者 |
山田, 崇史
× 山田, 崇史
× 和田, 正信
|
|||||||||||||
| アクセス権 | ||||||||||||||
| アクセス権 | open access | |||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||
| 権利情報 | ||||||||||||||
| 権利情報 | 日本体力医学会 | |||||||||||||
| 権利情報 | ||||||||||||||
| 権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | hyperthyroidism | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | contractile property | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | sarcoplasmic reticulum | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Ca^<2+> uptake rate | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | relaxation | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | NDC | |||||||||||||
| 主題 | 490 | |||||||||||||
| 内容記述 | ||||||||||||||
| 内容記述 | The effect of hyperthyroidism on the contractile properties and Ca^<2+> sequestering abilities by the sarcoplasmic reticulum (SR) in the soleus muscles was examined in rats treated with thyroid hormone (3, 5, 3'-triiodcrL-thyronine, T_3) (300μg/kg body weight) for 3, 7 and 21 days. At the end of a given treatment period, the right or left soleus muscle was mounted isometrically at 30℃, and stimulated directly using supramaximal current intensity. A twitch contraction was elicited by a 1 msec square-wave pulse and a tetanic contraction by 20 Hz stimulation for 600 msec. To evaluate fatigue resistance, muscles were stimulated at 40 Hz for 350msec with tetani repeated at an interval of 2 sec during a 4-min period. Another soleus muscle was used for analysis of SR Ca^<2+> -uptake rate and SR Ca^<2+> -ATPase activity. Pronounced increases in SR Ca^<2+> -uptake rate and ATPase activity were observed after T_3 treatment periods longer than 6 days. These alterations were accompanied by decreases in twitch and tetanic tension, half-relaxation time, and fatigue resistance. The T_<3-> treated muscles stimulated at 20 Hz relaxed during the interval between successive stimuli, indicating that the mechanical fusion of tetanic contractions was incomplete. SR Ca^<2+> uptake rate was significantly correlated both to tetanic tension and to fatigue resistance. These data suggest that there may be a causal relationship between changes in SR Ca^<2+> uptake and the loss of muscular strength in the hyperthyroid soleus. | |||||||||||||
| 言語 | en | |||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | 日本体力医学会 | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | jpn | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
| 関連情報 | ||||||||||||||
| 識別子タイプ | NAID | |||||||||||||
| 関連識別子 | 110001915734 | |||||||||||||
| 収録物識別子 | ||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 0039-906X | |||||||||||||
| 収録物識別子 | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AN00137986 | |||||||||||||
| 開始ページ | ||||||||||||||
| 開始ページ | 509 | |||||||||||||
| 書誌情報 |
体力科学 : Japanese Journal of Physical Fitness and Sports Medicine 体力科学 : Japanese Journal of Physical Fitness and Sports Medicine 巻 53, 号 5, p. 509-517, 発行日 2004-10-01 |
|||||||||||||
| 旧ID | 26003 | |||||||||||||
