| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
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|
タイトル |
Specific antibiotic prophylaxis based on bile cultures is required to prevent postoperative infectious complications in pancreatoduodenectomy patients who have undergone preoperative biliary drainage |
|
言語 |
en |
| 作成者 |
Sudo, Takeshi
Murakami, Yoshiaki
Uemura, Kenichiro
Hayashidani, Yasuo
Hashimoto, Yasushi
Ohge, Hiroki
Sueda, Taijiro
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
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|
権利情報 |
Copyright(c) 2007 Springer |
| 主題 |
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主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
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内容記述 |
Background Preoperative biliary drainage (PBD) is associated with bacterial contamination of bile, but the effects of PBD on morbidity after pancreatoduodenectomy remain controversial. The aim of this study was to characterize bile contamination to develop successful specific antibiotic prophylactic strategies for pancreatoduodenectomy. Methods Ninety-one consecutive patients who underwent pancreatoduodenectomy for periampullary tumor were prospectively evaluated. Prophylactic antibiotics were selected based on preoperative bile cultures. Bile cultures and postoperative complications were compared in 46 patients who underwent PBD (drainage group) versus 45 patients who did not (nondrainage group). Results The incidence of positive bile cultures was higher in the drainage group (78%) than in the nondrainage group (36%) (P < 0.001). In the drainage group, positive bile cultures were frequently polymicrobial (61%) and demonstrated resistance to several antibiotics, including cefazolin (83%), cefmetazole (72%), and cefpirome (64%). Overall morbidity (30-0x1.fd580000008p+0nd 22%) and infectious morbidity (13 0x1.f72676b636142p+855nd 11%) did not differ significantly between the drainage and nondrainage groups, respectively. Conclusions PBD had a notable influence on bile microbial contamination, including a higher rate of antibiotic resistance. Therefore, specific antibiotic prophylaxis based on bile culture is required for preventing infectious complications in pancreatoduodenectomy patients who undergo PBD. |
|
言語 |
en |
| 出版者 |
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|
出版者 |
Springer |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
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|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
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関連名称 |
The original publication is available at www.springerlink.com |
| 関連情報 |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1007/s00268-007-9210-4 |
| 関連情報 |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
http://dx.doi.org/10.1007/s00268-007-9210-4 |
| 収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0364-2313 |
| 収録物識別子 |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0089099X |
| 開始ページ |
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|
開始ページ |
2230 |
| 書誌情報 |
World Journal of Surgery
World Journal of Surgery
巻 31,
号 11,
p. 2230-2235,
発行日 2007-11
|
| 旧ID |
21467 |
WJS_31_2230.pdf (37.9 KB)
