| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2025-01-21 |
| タイトル |
|
|
タイトル |
Seasonal Influence on Development of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Retrospective Cohort Study Conducted at Multiple Institutions in Japan (J-CANVAS) |
|
言語 |
en |
| 作成者 |
Yoshida, Yusuke
Nakamoto, Naoki
Oka, Naoya
Kidoguchi, Genki
Hosokawa, Yohei
Araki, Kei
Ishitoku, Michinori
Watanabe, Hirofumi
Sugimoto, Tomohiro
Mokuda, Sho
Kida, Takashi
Yajima, Nobuyuki
Omura, Satoshi
Nakagomi, Daiki
Abe, Yoshiyuki
Kadoya, Masatoshi
Takizawa, Naoho
Nomura, Atsushi
Kukida, Yuji
Kondo, Naoya
Yamano, Yasuhiko
Yanagida, Takuya
Endo, Koji
Matsui, Kiyoshi
Takeuchi, Tohru
Ichinose, Kunihiro
Kato, Masaru
Yanai, Ryo
Matsuo, Yusuke
Shimojima, Yasuhiro
Nishioka, Ryo
Okazaki, Ryota
Takata, Tomoaki
Ito, Takafumi
Moriyama, Mayuko
Takatani, Ayuko
Miyawaki, Yoshia
Ito-Ihara, Toshiko
Kawaguchi, Takashi
Kawahito, Yutaka
Hirata, Shintaro
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
Copyright © 2023 by the Journal of Rheumatology |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is a pre-copyediting, author-produced PDF of an article accepted for publication in The Journal of Rheumatology following peer review. The definitive publisher-authenticated version Seasonal Influence on Development of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Retrospective Cohort Study Conducted at Multiple Institutions in Japan (J-CANVAS), Yusuke Yoshida et al, The Journal of Rheumatology, September 2023, 50 (9) 1152-1158 is available online at: https://doi.org/10.3899/jrheum.2023-0040. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is not the published version. Please cite only the published version. |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
antineutrophil cytoplasmic antibody |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
antineutrophil cytoplasmic antibody–associated vasculitis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
eosinophilic granulomatosis with polyangiitis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
granulomatosis with polyangiitis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
microscopic polyangiitis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
seasonal variation |
| 内容記述 |
|
|
内容記述 |
Objective To clarify seasonal and other environmental effects on the onset of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). Methods We enrolled patients with new-onset eosinophilic granulomatosis with polyangiitis (EGPA), microscopic polyangiitis (MPA), and granulomatosis with polyangiitis (GPA) registered in the database of a Japanese multicenter cohort study. We investigated the relationship between environmental factors and clinical characteristics. Seasons were divided into 4 (spring, summer, autumn, and winter), and the seasonal differences in AAV onset were analyzed using Pearson chi-square test, with an expected probability of 25% for each season. Results A total of 454 patients were enrolled, with a mean age of 70.9 years and a female proportion of 55.5%. Overall, 74, 291, and 89 patients were classified as having EGPA, MPA, and GPA, respectively. Positivity for myeloperoxidase (MPO)-ANCA and proteinase 3 (PR3)-ANCA was observed in 355 and 46 patients, respectively. Overall, the seasonality of AAV onset significantly deviated from the expected 25% for each season (P = 0.001), and its onset was less frequently observed in autumn. In ANCA serotypes, seasonality was significant in patients with MPO-ANCA (P < 0.001), but not in those with PR3-ANCA (P = 0.97). Additionally, rural residency of patients with AAV was associated with PR3-ANCA positivity and biopsy-proven pulmonary vasculitis. Conclusion The onset of AAV was influenced by seasonal variations and was less frequently observed in autumn. In contrast, the occurrence of PR3-ANCA was triggered, not by season, but by rural residency. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Journal of Rheumatology |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3899/jrheum.2023-0040 |
| 開始ページ |
|
|
開始ページ |
1152 |
| 書誌情報 |
en : The Journal of Rheumatology
巻 50,
号 9,
p. 1152-1158,
発行日 2023-09-01
|
| 旧ID |
56137 |
JRheumatology_50_1152.pdf (1.1 MB)
