Item type |
デフォルトアイテムタイプ_(フル)(1) |
公開日 |
2023-03-18 |
タイトル |
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タイトル |
A pilot study of the multiherb Kampo medicine bakumondoto for cough in patients with chronic obstructive pulmonary disease |
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言語 |
en |
作成者 |
Mukaida, Kenichi
Hattori, Noboru
Kondo, Keiichi
Morita, Naoki
Murakami, Isao
Haruta, Yoshihiro
Yokoyama, Akihito
Kohno, Nobuoki
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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権利情報 |
(c) 2010 Elsevier GmbH. All rights reserved. |
主題 |
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主題Scheme |
Other |
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主題 |
Bakumondoto |
主題 |
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主題Scheme |
Other |
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主題 |
Multiherb Kampo medicine |
主題 |
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主題Scheme |
Other |
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主題 |
Pilot study |
主題 |
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主題Scheme |
Other |
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主題 |
Cough |
主題 |
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主題Scheme |
Other |
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主題 |
Chronic obstructive pulmonary disease (COPD) |
主題 |
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主題Scheme |
NDC |
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主題 |
490 |
内容記述 |
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内容記述 |
Objectives: To evaluate the effect of bakumondoto. Kampo medicine, on cough in patients with chronic obstructive pulmonary disease (COPD). Design: A 16-week, randomized, open-labeled, cross-over design. Setting: Outpatient clinics at one university hospital and two general hospitals in Japan from May 2007 to March 2009. Participants: Twenty-four elderly patients (14 men and 9 women aged over 65) with COPD. Intervention: Treatment with or without bakumondoto for 8 weeks in a cross-over design. Measurements: The primary outcome measurements were the frequency and intensity of cough assessed by a visual analogue scale (VAS) and a daily cough diary. Secondary outcome measurements were quality of life (QOL) assessed using St. George's Respiratory Questionnaire (SGRQ) and lung functions measured using spirometry. Results: Treatment with bakumondoto significantly improved cough severity during the first treatment period (week 0 vs. week 8, p = 0.004) and showed a trend to decrease during the second treatment period (week 8 vs. week16, p=0.129) assessed by the VAS. Neither QOL nor lung function was affected by the treatment with bakumondoto. Conclusion: Bakumondoto may be effective in suppressing cough in elderly patients with COPD. To further confirm the efficacy, a larger and placebo-controlled study with objective cough assessment is necessary. |
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言語 |
en |
出版者 |
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出版者 |
Elsevier GmbH - Urban & Fischer Verlag |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
AO |
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出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
10.1016/j.phymed.2010.11.006 |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
http://dx.doi.org/10.1016/j.phymed.2010.11.006 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0944-7113 |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11016697 |
開始ページ |
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開始ページ |
625 |
書誌情報 |
Phytomedicine
Phytomedicine
巻 18,
号 8-9,
p. 625-629,
発行日 2011
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旧ID |
34829 |