| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Immunohistochemical marker panels for distinguishing between epithelioid mesothelioma and lung adenocarcinoma |
|
言語 |
en |
| 作成者 |
Kushitani, Kei
Takeshima, Yukio
Amatya, Vishwa Jeet
Furonaka, Osamu
Sakatani, Akio
Inai, Kouki
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2007 Blackwell Publishing. The definitive version is available at www.blackwell-synergy.com |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
adenocarcinoma |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
calretinin |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
CEA |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
immunohistochemistry |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
mesothelioma |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
thrombomodulin |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
WT1 |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
The distinction between epithelioid mesothelioma and lung adenocarcinoma remains an important diagnostic challenge for surgical pathologists. The aim of the present study was to select a limited and appropriate panel of antibodies that can differentiate between epithelioid mesothelioma and lung adenocarcinoma. Specimens of 90 epithelioid mesotheliomas and 51 lung adenocarcinomas obtained from Japanese cases were examined using calretinin, WT1, AE1/AE3, CAM5.2, cytokeratin (CK) 5/6, vimentin, epithelial membrane antigen (EMA), thrombomodulin, CEA, CA19-9, and CA125. Ninety-six percent of epithelioid mesotheliomas were positive for calretinin; 99% for WT1; 100% for AE1/AE; 97% for CAM5.2; 70% for CK 5/6; 91% for vimentin; 96% for EMA; 71% for thrombomodulin; 77% for mesothelin; 7% for CEA; 17% for CA19-9; and 85% for CA125. In contrast, 33% of lung adenocarcinomas were positive for calretinin; 16% for WT1; 100% for AE1/AE3, CAM5.2, and EMA; 41% for CK 5/6; 47% for vimentin; 20% for thrombomodulin; 69% for mesothelin; 98% for CEA; 73% for CA19-9; and 80% for CA125. For distinguishing between epithelioid mesothelioma and lung adenocarcinoma, the combination of CEA, calretinin and each WT1 or thrombomodulin was suggested to be the best panel of immunohistochemical markers. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Blackwell Publishing |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1111/j.1440-1827.2007.02080.x |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1111/j.1440-1827.2007.02080.x |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1320-5463 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10984364 |
| 開始ページ |
|
|
開始ページ |
190 |
| 書誌情報 |
Pathology International
Pathology International
巻 57,
号 4,
p. 190-199,
発行日 2007-04
|
| 旧ID |
20579 |
PatholInt_57-4_190.pdf (906.9 KB)
