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Different stabilities of liposomes containing saturated and unsaturated lipids toward the addition of cyclodextrins
https://hiroshima.repo.nii.ac.jp/records/2007915
https://hiroshima.repo.nii.ac.jp/records/20079159c6a67cd-359f-4af0-8f00-fe59706c5adb
名前 / ファイル | ライセンス | アクション |
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Item type | デフォルトアイテムタイプ_(フル)(1) | |||||||||||
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公開日 | 2023-03-18 | |||||||||||
タイトル | ||||||||||||
タイトル | Different stabilities of liposomes containing saturated and unsaturated lipids toward the addition of cyclodextrins | |||||||||||
言語 | en | |||||||||||
作成者 |
Ikeda, Atsushi
× Ikeda, Atsushi
× Funada, Rikushi
× Sugikawa, Kouta
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アクセス権 | ||||||||||||
アクセス権 | open access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
権利情報 | ||||||||||||
権利情報 | Copyright (c) 2016 The Royal Society of Chemistry | |||||||||||
権利情報 | ||||||||||||
権利情報 | This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | |||||||||||
主題 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 430 | |||||||||||
内容記述 | ||||||||||||
内容記述 | Liposomes composed of unsaturated lipids were more stable than those containing saturated lipids toward DMe‐β‐CDx, DMe‐α‐CDx and DMe‐β‐CDx. The Hill coefficient values (n) indicated that the saturated lipid•DMe‐CDx complexes had stoichiometric ratios in the range of 1:3‒1:4, while the unsaturated lipid•DMe‐CDx complexes had ratios in the range of 1:1.5‒1:3. That is, a cis alkene group in the unsaturated lipids prevented complexation with a second DMe‐CDx in the direction toward each acyl chain. Furthermore, the liposomes composed of the unsaturated lipids were much slower to form precipitates upon the addition of α‐CDx than those of the saturated lipids. To the best of our knowledge, this is the first example showing that CDxs interact with unsaturated lipids. | |||||||||||
言語 | en | |||||||||||
内容記述 | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | This work was supported by the Japanese Society for the Promotion of Science (JSPS) KAKENHI a Grant‐in‐Aid for Scientific Research (B) (Grant No. 25288037 and No. 16H04133) and a Grant‐in‐Aid for Challenging Exploratory Research (Grant No. 16K13982). | |||||||||||
出版者 | ||||||||||||
出版者 | Royal Society of Chemistry | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
出版タイプ | ||||||||||||
出版タイプ | AO | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_b1a7d7d4d402bcce | |||||||||||
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識別子タイプ | DOI | |||||||||||
関連識別子 | 10.1039/c6ob00535g | |||||||||||
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識別子タイプ | PMID | |||||||||||
関連識別子 | 27181919 | |||||||||||
収録物識別子 | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1477-0520 | |||||||||||
開始ページ | ||||||||||||
開始ページ | 5065 | |||||||||||
書誌情報 |
Organic and Biomolecular Chemistry Organic and Biomolecular Chemistry 巻 14, 号 22, p. 5065-5072, 発行日 2016-06-04 |
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旧ID | 46202 |