| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Improvement of constipation and liver function by plant-derived lactic acid bacteria : A double-blind, randomized trial |
|
言語 |
en |
| 作成者 |
Higashikawa, Fumiko
Noda, Masafumi
Awaya, Tomokazu
Nomura, Kazuhiro
Oku, Hirotaka
Sugiyama, Masanori
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2010 Elsevier B.V. |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Probiotics |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Lactobacillus plantarum |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Defecation |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Cholesterol |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
gamma-Glutamyl transpeptidase |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Objective: Lactic acid bacteria (LAB) contribute to human health; however, the probiotic properties vary among strains classified into the same species. The primary objective of this study was to evaluate the effects of yogurts made by different types of LAB on the gastrointestinal system. The yogurts are also evaluated by measuring serum lipid contents and liver functional indicators as secondary objective. Methods: Healthy human adults (n=68) with some complaints with regard to intestinal health, including constipation and diarrhea, were randomly assigned to receive one of three types of yogurt in a double-blind manner: (type A) yogurt made by plant-derived LAB (mainly Lactobacillus (Lb.) plantarum SN35N); (type B) yogurt made by plant-derived LAB (mainly Lb. plantarum SN13T); (type C) yogurt made by animal-derived LAB (mainly Lactococcus lactis A6 and Streptococcus thermophilus 510) as a control. The subjects consumed 100g of yogurt daily for 6 weeks. Data were collected from clinical visits at 2-week intervals and by diaries used to record defecation and health conditions. Results: Drastic and constant increments of defecation frequency in subjects with constipation were observed with type A and B yogurts but not with type C yogurt. Type B and C yogurts resulted in decreases in total and LDL cholesterol. The serum concentrations of liver functional parameters were improved by the type B yogurt (12-25% reduction). Conclusions: The present study suggests that Lb. plantarum SN13T exhibits a superior probiotic effect on constipation in addition to improving the serum lipid contents and liver function. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Elsevier Science INC |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.nut.2009.05.008 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1016/j.nut.2009.05.008 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0899-9007 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10745727 |
| 開始ページ |
|
|
開始ページ |
367 |
| 書誌情報 |
Nutrition
Nutrition
巻 26,
号 4,
p. 367-374,
発行日 2010-04
|
| 旧ID |
30417 |
Nutrition_26_367.pdf (189.2 KB)
