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Improvement of constipation and liver function by plant-derived lactic acid bacteria : A double-blind, randomized trial

https://hiroshima.repo.nii.ac.jp/records/2007891
https://hiroshima.repo.nii.ac.jp/records/2007891
6db3520b-f99b-43d3-b3f8-088985b4ac04
名前 / ファイル ライセンス アクション
Nutrition_26_367.pdf Nutrition_26_367.pdf (189.2 KB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル Improvement of constipation and liver function by plant-derived lactic acid bacteria : A double-blind, randomized trial
言語 en
作成者 Higashikawa, Fumiko

× Higashikawa, Fumiko

en Higashikawa, Fumiko

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Noda, Masafumi

× Noda, Masafumi

en Noda, Masafumi

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Awaya, Tomokazu

× Awaya, Tomokazu

en Awaya, Tomokazu

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Nomura, Kazuhiro

× Nomura, Kazuhiro

en Nomura, Kazuhiro

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Oku, Hirotaka

× Oku, Hirotaka

en Oku, Hirotaka

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Sugiyama, Masanori

× Sugiyama, Masanori

en Sugiyama, Masanori

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
権利情報 Copyright (c) 2010 Elsevier B.V.
主題
主題Scheme Other
主題 Probiotics
主題
主題Scheme Other
主題 Lactobacillus plantarum
主題
主題Scheme Other
主題 Defecation
主題
主題Scheme Other
主題 Cholesterol
主題
主題Scheme Other
主題 gamma-Glutamyl transpeptidase
主題
主題Scheme NDC
主題 490
内容記述
内容記述 Objective: Lactic acid bacteria (LAB) contribute to human health; however, the probiotic properties vary among strains classified into the same species. The primary objective of this study was to evaluate the effects of yogurts made by different types of LAB on the gastrointestinal system. The yogurts are also evaluated by measuring serum lipid contents and liver functional indicators as secondary objective. Methods: Healthy human adults (n=68) with some complaints with regard to intestinal health, including constipation and diarrhea, were randomly assigned to receive one of three types of yogurt in a double-blind manner: (type A) yogurt made by plant-derived LAB (mainly Lactobacillus (Lb.) plantarum SN35N); (type B) yogurt made by plant-derived LAB (mainly Lb. plantarum SN13T); (type C) yogurt made by animal-derived LAB (mainly Lactococcus lactis A6 and Streptococcus thermophilus 510) as a control. The subjects consumed 100g of yogurt daily for 6 weeks. Data were collected from clinical visits at 2-week intervals and by diaries used to record defecation and health conditions. Results: Drastic and constant increments of defecation frequency in subjects with constipation were observed with type A and B yogurts but not with type C yogurt. Type B and C yogurts resulted in decreases in total and LDL cholesterol. The serum concentrations of liver functional parameters were improved by the type B yogurt (12-25% reduction). Conclusions: The present study suggests that Lb. plantarum SN13T exhibits a superior probiotic effect on constipation in addition to improving the serum lipid contents and liver function.
言語 en
出版者
出版者 Elsevier Science INC
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ AO
出版タイプResource http://purl.org/coar/version/c_b1a7d7d4d402bcce
関連情報
識別子タイプ DOI
関連識別子 10.1016/j.nut.2009.05.008
関連情報
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.1016/j.nut.2009.05.008
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0899-9007
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA10745727
開始ページ
開始ページ 367
書誌情報 Nutrition
Nutrition

巻 26, 号 4, p. 367-374, 発行日 2010-04
旧ID 30417
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