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A systematic search and classification of T2 family miniature inverted-repeat transposable elements (MITEs) in Xenopus tropicalis suggests the existence of recently active MITE subfamilies

https://hiroshima.repo.nii.ac.jp/records/2007728
https://hiroshima.repo.nii.ac.jp/records/2007728
4f848031-5871-4321-a977-7c05a24ea5d8
名前 / ファイル ライセンス アクション
MolGenetGenom_283_49.pdf MolGenetGenom_283_49.pdf (2.1 MB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル A systematic search and classification of T2 family miniature inverted-repeat transposable elements (MITEs) in Xenopus tropicalis suggests the existence of recently active MITE subfamilies
言語 en
作成者 Hikosaka, Akira

× Hikosaka, Akira

en Hikosaka, Akira

Search repository
Kawahara, Akira

× Kawahara, Akira

en Kawahara, Akira

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
権利情報 Copyright (c) 2009 Springer
主題
主題Scheme Other
主題 Transposon
主題
主題Scheme Other
主題 Miniature inverted-repeat transposable element (MITE)
主題
主題Scheme Other
主題 T2 family
主題
主題Scheme Other
主題 Xenopus
主題
主題Scheme NDC
主題 490
内容記述
内容記述 To reveal the genome-wide aspects of Xenopus T2 family miniature inverted-repeat transposable elements (MITEs), we performed a systematic search and classification of MITEs by a newly developed procedure. A terminal sequence motif (T2-motif: TTAAAGGRR) was retrieved from the Xenopus tropicalis genome database. We then selected 51- to 1,000-bp MITE candidates framed by an inverted pair of 2 T2-motifs. The 34,398 candidates were classified into possible clusters by a novel terminal sequence (TS)-clustering method on the basis of differences in their short terminal sequences. Finally, 19,242 MITEs were classified into 16 major MITE subfamilies (TS subfamilies), 10 of which showed apparent homologies to known T2 MITE subfamilies, and the rest were novel TS subfamilies. Intra-and inter-subfamily similarities or differences were investigated by analyses of diversity in GC content, total length, and sequence alignments. Furthermore, genome-wide conservation of the inverted pair structure of subfamily-specific TS stretches and their target site sequence (TTAA) were analyzed. The results suggested that some TS subfamilies might include active or at least recently active MITEs for transposition and/or amplification, but some others might have lost such activities a long time ago. The present methodology was efficient in identifying and classifying MITEs, thereby providing information on the evolutionary dynamics of MITEs.
言語 en
出版者
出版者 Springer Heidelberg
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ AO
出版タイプResource http://purl.org/coar/version/c_b1a7d7d4d402bcce
関連情報
関連名称 The original publication is available at www.springerlink.com
関連情報
識別子タイプ DOI
関連識別子 10.1007/s00438-009-0496-9
関連情報
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.1007/s00438-009-0496-9
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1617-4615
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA11547886
開始ページ
開始ページ 49
書誌情報 Molecular Genetics and Genomics
Molecular Genetics and Genomics

巻 283, 号 1, p. 49-62, 発行日 2009-11-13
旧ID 29226
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