| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2025-01-21 |
| タイトル |
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タイトル |
Effects of the Molecular Structure of Malodor Substances and Their Masking on 1,2-Dioleoyl-sn-glycero-3-phosphocholine Molecular Layers |
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言語 |
en |
| 作成者 |
Yotsumoto, Mai
Fujita, Risa
Matsuo, Muneyuki
Nakanishi, Shinobu
Denda, Mitsuhiro
Nakata, Satoshi
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
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言語 |
en |
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権利情報 |
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Langmuir, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.langmuir.3c03796 |
| 権利情報 |
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言語 |
en |
|
権利情報 |
This is not the published version. Please cite only the published version. |
| 権利情報 |
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言語 |
ja |
|
権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
| 内容記述 |
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内容記述 |
Certain odors have been shown not only to cause health problems and stress but also to affect skin barrier function. Therefore, it is important to understand olfactory masking to develop effective fragrances to mask malodors. However, olfaction and olfactory masking mechanisms are not yet fully understood. To understand the mechanism of the masking effect that has been studied, the responses of several target substance (TS) molecules–1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) mixed molecular layers to odorant (OD) molecules were examined as a simple experimental model of epithelial cellular membranes injured by TS molecules. Here, we examined trans-2-nonenal, 1-nonanal, trans-2-decenal, and 1-decanal as TS molecules to clarify the effects of double bonds and hydrocarbon chain lengths on the phospholipid molecular layer. In addition, benzaldehyde and cyclohexanecarboxaldehyde were utilized as OD molecules to clarify the masking effect of the aromatic ring. Surface pressure (Π)–area (A) isotherms were measured to clarify the adsorption or desorption of TS and OD molecules on the DOPC molecular layer. In addition, Fourier transform infrared spectroscopy was performed to clarify the interactions among DOPC, TS, and OD molecules. We found that TS molecules with and without double bonds had different effects on the DOPC molecular layer and that molecules with shorter chain lengths had greater effects on the DOPC molecular layer. Furthermore, OD molecules with aromatic rings counteracted the effects of the TS molecules. On the basis of this research, not only a detailed mechanism by which odor molecules affect lipid membranes without mediating olfactory receptors is elucidated but also more effective OD molecules with masking effects are proposed. |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Other |
|
内容記述 |
This study was supported by the Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research (KAKENHI) (Grants JP20H02712 and JP21H00996), the Iketani Science and Technology Foundation (0351181-A), the Cooperative Research Program of “Network Joint Research Center for Materials and Devices" (20231004) to Satoshi Nakata, and the JSPS Bilateral Joint Research Project between Japan and Hungary (JPJSBP120213801). This study was supported by a Sasakawa Scientific Research Grant from the Japan Science Society Award (2023-6004) and the Japan Science and Technology Agency (JST) for the establishment of university fellowships toward the creation of science technology innovation (JPMJFS2129) to Mai Yotsumoto. |
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言語 |
en |
| 出版者 |
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出版者 |
American Chemical Society |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版タイプ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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|
関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1021/acs.langmuir.3c03796 |
| 助成情報 |
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助成機関名 |
日本学術振興会 |
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言語 |
ja |
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研究課題番号URI |
https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-20H02712/ |
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研究課題番号 |
20H02712 |
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研究課題名 |
時空間発展する自己駆動体の構築 |
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言語 |
ja |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science |
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言語 |
en |
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研究課題番号URI |
https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-23K20808/ |
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研究課題番号 |
21H00996 |
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研究課題名 |
Spatiotemporally developed self-propelled objects |
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言語 |
en |
| 助成情報 |
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助成機関名 |
日本学術振興会 |
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言語 |
ja |
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研究課題名 |
自己駆動体の集団運動に対する数理モデリングと数理解析 |
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言語 |
ja |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science |
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言語 |
en |
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研究課題名 |
自己駆動体の集団運動に対する数理モデリングと数理解析 |
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言語 |
ja |
| 開始ページ |
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開始ページ |
6878 |
| 書誌情報 |
en : Langmuir
巻 40,
号 13,
p. 6878-6883,
発行日 2024-03-19
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| 旧ID |
56138 |
Langmuir_40_6878.pdf (1.0 MB)
