| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
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タイトル |
A novel peroxisomal nonspecific lipid-transfer protein from Candida tropicalis. Gene structure, purification and possible role in β-oxidation |
|
言語 |
en |
| 作成者 |
Tan, Hironobu
Okazaki, Koei
Kubota, Ichiro
Kamiryo, Tatsuyuki
Utiyama, Hiroyasu
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
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|
権利情報 |
Copyright (c) 1990 Federation of European Biochemical Societies |
| 主題 |
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主題Scheme |
NDC |
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主題 |
460 |
| 内容記述 |
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内容記述 |
We have sequenced the nucleotides of the gene POX18 that encodes PXP-18, a major peroxisomal polypeptide inducible by oleic acid in the yeast Candida tropicalis. POX18 had a single open reading frame of 127 amino acids. Some 330f the amino acid sequence of the predicted basic polypeptide (13805 Da), was identical to that of the nonspecific lipid-transfer protein (sterol carrier protein 2) from rat liver. PXP-18, purified to near homogeneity from isolated peroxisomes, had an amino-terminal sequence identical to that of the predicted polypeptide except for the initiator methionine, and had nonspecific lipid-transfer activity comparable to that of its mammalian equivalents. Unexpectedly, PXP-18 lacked the cysteine residue thought to be essential for the activity of this protein in mammals. RNA blot analysis showed that the POX18 gene was expressed exclusively in cells grown on oleic acid, suggesting that PXP-18 has a role in the β-oxidation of long-chain fatty acids. PXP-18 modulated acyl-coenzyme A oxidase activity at low pH. |
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言語 |
en |
| 出版者 |
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出版者 |
Federation of European Biochemical Societies |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AO |
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出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
10.1111/j.1432-1033.1990.tb15552.x |
| 関連情報 |
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識別子タイプ |
PMID |
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関連識別子 |
2364939 |
| 関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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|
関連識別子 |
http://dx.doi.org/10.1111/j.1432-1033.1990.tb15552.x |
| 収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0014-2956 |
| 収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00639541 |
| 開始ページ |
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開始ページ |
107 |
| 書誌情報 |
European Journal of Biochemistry
European Journal of Biochemistry
巻 190,
号 1,
p. 107-122,
発行日 1990
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| 旧ID |
14885 |
ejb_190_107.pdf (772.1 KB)
