| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2025-01-14 |
| タイトル |
|
|
タイトル |
Characteristics and Prognosis of Sporadic Neoplasias Detected in Patients with Ulcerative Colitis |
|
言語 |
en |
| 作成者 |
Yamamoto, Noriko
Yamashita, Ken
Takehara, Yudai
Morimoto, Shin
Tanino, Fumiaki
Kamigaichi, Yuki
Tanaka, Hidenori
Arihiro, Koji
Shimamoto, Fumio
Oka, Shiro
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
The final, published version of this article is available at https://karger.com/?doi=10.1159/000537756. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is not the published version. Please cite only the published version. |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Ulcerative colitis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Sporadic neoplasia |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Ulcerative colitis-associated neoplasia |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Metachronous lesion |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Characteristics |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Prognosis |
| 内容記述 |
|
|
内容記述 |
Introduction: Patients with ulcerative colitis (UC) develop not only UC-associated neoplasias but also sporadic neoplasias (SNs). However, few studies have described the characteristics of SNs in patients with UC. Therefore, this study aimed to evaluate the clinical features and prognosis of SNs in patients with UC. Methods: A total of 141 SNs in 59 patients with UC, detected by surveillance colonoscopy at Hiroshima University Hospital between January 1999 and December 2021, were included. SNs were diagnosed based on their location, endoscopic features, and histopathologic findings along with immunohistochemical staining for Ki67 and p53. Results: Of the SNs, 91.5% were diagnosed as adenoma and 8.5% were diagnosed as carcinoma (Tis carcinoma, 3.5%; T1 carcinoma, 5.0%). 61.0% of the SNs were located in the right colon, 31.2% were located in the left colon, and 7.8% were located in the rectum. When classified based on the site of the lesion, 70.9% of SNs occurred outside and 29.1% within the affected area. Of all SNs included, 95.7% were endoscopically resected and 4.3% were surgically resected. Among the 59 patients included, synchronous SNs occurred in 23.7% and metachronous multiple SNs occurred in 40.7% during surveillance. The 5-year cumulative incidence of metachronous multiple SNs was higher in patients with synchronous multiple SNs (54.2%) than in those without synchronous multiple SNs (46.4%). Conclusion: Patients with UC with synchronous multiple SNs are at a higher risk of developing metachronous multiple SNs and may require a closer follow-up by total colonoscopy than patients without synchronous SNs. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Karger |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1159/000537756 |
| 開始ページ |
|
|
開始ページ |
213 |
| 書誌情報 |
en : Digestion
巻 105,
号 3,
p. 213-223,
発行日 2024-02-28
|
| 旧ID |
56112 |
Digestion_105_213.pdf (1.4 MB)
