| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
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|
タイトル |
Molecular characterization of lipoprotein lipase, hepatic lipase and pancreatic lipase genes and effects of fasting and refeeding on their gene expression in red sea bream Pagrus major |
|
言語 |
en |
| 作成者 |
Oku, Hiromi
Koizumi, Naoto
Okumura, Takuji
Kobayashi, Takanori
Umino, Tetsuya
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| アクセス権 |
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|
アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2006 Elsevier Ltd. |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
teleost |
| 主題 |
|
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主題Scheme |
Other |
|
主題 |
red sea bream |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
Pagrus major |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
LPL |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
HL |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
PL |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
nutritional regulation |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
molecular cloning |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
660 |
| 内容記述 |
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|
内容記述 |
To investigate the nutritional regulation of lipid metabolism in fish, molecular characterization of lipases was conducted in red sea bream Pagrus major, and the effects of fasting and refeeding on their gene expression was examined. Taken together with our previous study (LPL2: Oku et al. 2002, Comp. Biochem. Physiol. 131B, 775-783), four lipase genes were identified and characterized as lipoprotein lipase (LPL), hepatic lipase (HL) and pancreatic lipase (PL). These four lipase genes, termed LPL1, LPL2, HL and PL, share a high degree of similarity with each other. Both LPL1 and LPL2 genes were expressed in various tissues including adipose tissue, gill, heart and hepatopancreas. HL gene was exclusively expressed in hepatopancreas. PL gene expression was detected in hepatopancreas and adipose tissue. Red sea bream LPL1 and LPL2 gene expression levels in hepatopancreas were increased during 48 hr fasting and decreased after refeeding, whereas no significant change in the expression levels of LPL1 and LPL2 was observed in adipose tissue, indicating that LPL1 and LPL2 gene expression is regulated in a tissue-specific manner in response to the nutritional state of fish. HL and PL gene expression was not affected by fasting and refeeding. The results of this study suggested that LPL, HL and PL gene expression is under different regulatory mechanisms in red sea bream with respect to the tissue-specificities and their nutritional regulation. |
|
言語 |
en |
| 出版者 |
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|
出版者 |
Elsevier |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.1016/j.cbpb.2006.06.008 |
| 関連情報 |
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|
識別子タイプ |
PMID |
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関連識別子 |
16904358 |
| 関連情報 |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1016/j.cbpb.2006.06.008 |
| 収録物識別子 |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1096-4959 |
| 収録物識別子 |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11045017 |
| 開始ページ |
|
|
開始ページ |
168 |
| 書誌情報 |
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
巻 145,
号 2,
p. 168-178,
発行日 2006-10
|
| 旧ID |
17057 |
CBP_145_168.pdf (1.3 MB)
