WEKO3
アイテム
ウニ形態形成に関わる母系因子の研究
https://hiroshima.repo.nii.ac.jp/records/2005313
https://hiroshima.repo.nii.ac.jp/records/20053134522366e-b99b-451a-806a-4501b55c4c06
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
diss_ko1981.pdf (30.0 MB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||
| タイトル | ||||||||||
| タイトル | Maternal factors related to body plan of sea urchin | |||||||||
| 言語 | en | |||||||||
| タイトル | ||||||||||
| タイトル | ウニ形態形成に関わる母系因子の研究 | |||||||||
| 言語 | ja | |||||||||
| 作成者 |
小川, 麻里
× 小川, 麻里
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| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 権利情報 | ||||||||||
| 権利情報 | Copyright(c) by Author | |||||||||
| 主題 | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 480 | |||||||||
| 内容記述 | ||||||||||
| 内容記述 | Expression of genes underlying various developmental processes such as morphogenesis, body plan, etc. is regulated by cascades of transcription factors. Factors or cell fate determinants of maternal origin are supposed to play important roles to drive these cascades. Sea urchin is one of the most useful material to study maternal factors and transcriptional cascades, because of simplicity of its developmental pattern and body plan and of easiness to get synchronized embryos in a large amount. In addition, the simple and quick procedure to introduce exogenous genes into a large number of sea urchin eggs has been developed in our laboratory. The study in the present thesis has been undertaken to identify some of the maternal factors of sea urchin eggs and to elucidate their role in sea urchin development. In Part 1 of this thesis, detection and identification of maternal factors, poly(A)+ mitochondrial ribosomal type RNA (mt 12S rRNA and mt 16S rRNA), asymmetrically enriched in small micromeres are described. These two mt rRNAs are localize outside of mitochondria and distinguished from intramitochondrial rRNAs. Based on this findings, the author speculates possible role of extramitochondrial mt rRNAs in sea urchin development. In Part II, the author has detected other maternal factor, HpSox protein, in sea urchin eggs, and found that by binding to a Sox motif in the promoter of the arylsulfatase gene HpSox protein regulates expression of arylsulfatase protein that is related to build up body plan of pluteus larvae. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | TableOfContents | |||||||||
| 内容記述 | Contents General Abstract / p1 General Introduction / p3 References / p6 Part I Asymmetrical distribution of mitochondrial rRNA into small micromeres of sea urchin embryos / p8 Abstract / p9 Introduction / p10 Materials and Methods / p12 Results / p17 Figures / p20 Discussion / p25 References / p28 Part II Sox and other regulatory elements in the promoter region of the sea urchin arylsulfatase Gene / p34 Abstract / p35 Introduction / p36 Materials and Methods / p38 Results / p41 Figures / p46 Discussion / p52 References / p55 | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| 関連情報 | ||||||||||
| 関連タイプ | references | |||||||||
| 関連名称 | Asymmetrical distribution of mitochondrial rRNA into small micromeres of sea urchin embryos. Mari Ogawa, Reiko Amikura, Koji Akasaka, Tsutomu Kinoshita, Satoru Kobayashi and Hiraku Shimada. accepted for Zoological Science | |||||||||
| 関連情報 | ||||||||||
| 関連タイプ | references | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | http://dx.doi.org/10.2108/zsj.16.445 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第1981号 | |||||||||
| 学位名 | ||||||||||
| 言語 | ja | |||||||||
| 学位名 | 博士(理学) | |||||||||
| 学位名 | ||||||||||
| 言語 | en | |||||||||
| 学位名 | Physical Science | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 1999-03-25 | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 15401 | |||||||||
| 言語 | ja | |||||||||
| 学位授与機関名 | 広島大学 | |||||||||
| 学位授与機関 | ||||||||||
| 言語 | en | |||||||||
| 学位授与機関名 | Hiroshima University | |||||||||
| 旧ID | 31926 | |||||||||
