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  1. 広島大学博士論文
  2. 2013年度

喫煙と眼底血管径の関連は禁煙後にも残るか

https://hiroshima.repo.nii.ac.jp/records/2005077
https://hiroshima.repo.nii.ac.jp/records/2005077
ce1af8e5-9185-4cfb-9a3f-54f87cef2c36
名前 / ファイル ライセンス アクション
k6288_3.pdf k6288_3.pdf (411.5 KB)
k6288_1.pdf k6288_1.pdf (255.6 KB)
k6288_2.pdf k6288_2.pdf (195.4 KB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル Is the association between smoking and the retinal venular diameter reversible following smoking cessation?
言語 en
タイトル
タイトル 喫煙と眼底血管径の関連は禁煙後にも残るか
言語 ja
作成者 柳, 昌秀

× 柳, 昌秀

ja 柳, 昌秀

en Yanagi, Masahide

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
主題
主題Scheme Other
主題 retinal vessels
主題
主題Scheme Other
主題 smoking
主題
主題Scheme Other
主題 microcirculation
主題
主題Scheme Other
主題 arterioles
主題
主題Scheme Other
主題 venules
主題
主題Scheme NDC
主題 490
内容記述
内容記述 PURPOSE. Wider retinal venular caliber is shown to be associated with an increased risk of stroke, and smoking is associated with a wider retinal venular caliber. However, the impact of smoking cessation on the retinal vessels has not been previously reported. We examined this issue in an adult cohort of atomic bomb survivors. METHODS. In the Adult Health Study of Japanese atomic bomb survivors, 1664 subjects had retinal photographs taken from 2006 to 2008. The central retinal artery and vein equivalents (CRAE and CRVE) were calculated using a semiautomated software program. Multiple surveys have assessed the effects of smoking since 1963. The associations between smoking, the time since cessation, and the retinal vessel caliber were determined using linear mixed effects models. RESULTS. The CRVE was associated with an increased number of cigarettes smoked per day among women after adjusting for potential confounding factors (age, sex, blood pressure, hypertensive medications, white blood cell count, diabetes, body mass index, lipids, and radiation dose). Females who smoked 10 cigarettes per day had a 6.9-lm wider mean CRVE (P = 0.001) than nonsmokers. Females who had stopped smoking for 10 or more years had a mean CRVE similar to those who had never smoked (191.8 vs. 194.4 lm; P = 0.23). These associations were not observed in males or for CRAE. CONCLUSIONS. Wider retinal venular caliber is associated with smoking in Japanese females; however, this association becomes nonsignificant after 10 or more years of smoking cessation, suggesting that the impact of smoking on retinal venular dilation is reversible following longterm smoking cessation.
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
資源タイプ doctoral thesis
出版タイプ
出版タイプ NA
出版タイプResource http://purl.org/coar/version/c_be7fb7dd8ff6fe43
関連情報
関連タイプ references
関連名称 Masahide Yanagi, Munechika Misumi, Ryo Kawasaki, Ikuno Takahashi, Katsumasa Itakura, Saeko Fujiwara, Masazumi Akahoshi, Kazuo Neriishi, Tien Yin Wong and Yoshiaki Kiuchi; Is the Association Between Smoking and the Retinal Venular Diameter Reversible Following Smoking Cessation?; Invest. Ophthalmol. Vis. Sci. January 21, 2014 vol.55 no.1 405-411 (DOI: 10.1167/iovs.13-12512)
関連情報
関連タイプ references
識別子タイプ DOI
関連識別子 http://doi.org/10.1167/iovs.13-12512
学位授与番号
学位授与番号 甲第6288号
学位名
言語 ja
学位名 博士(医学)
学位名
言語 en
学位名 Philosophy in Medical Science
学位授与年月日
学位授与年月日 2014-02-27
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 15401
言語 ja
学位授与機関名 広島大学
学位授与機関
言語 en
学位授与機関名 Hiroshima University
旧ID 40616
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