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In vitro organogenesis using amphibian pluripotential cells
https://hiroshima.repo.nii.ac.jp/records/2000945
https://hiroshima.repo.nii.ac.jp/records/2000945f61a3937-9f78-4ab1-a0a0-b3fcef656790
名前 / ファイル | ライセンス | アクション |
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Item type | デフォルトアイテムタイプ_(フル)(1) | |||||||||
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公開日 | 2023-03-18 | |||||||||
タイトル | ||||||||||
タイトル | In vitro organogenesis using amphibian pluripotential cells | |||||||||
言語 | en | |||||||||
作成者 |
Asashima, Makoto
× Asashima, Makoto
× Okabayashi, K.
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アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
主題 | ||||||||||
主題Scheme | Other | |||||||||
主題 | activin | |||||||||
主題 | ||||||||||
主題Scheme | Other | |||||||||
主題 | organogenesis | |||||||||
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主題Scheme | Other | |||||||||
主題 | animal cap | |||||||||
主題 | ||||||||||
主題Scheme | Other | |||||||||
主題 | mesoderm induction | |||||||||
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主題Scheme | Other | |||||||||
主題 | organizer | |||||||||
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主題Scheme | NDC | |||||||||
主題 | 490 | |||||||||
内容記述 | ||||||||||
内容記述 | In the embryonic development of vertebrate, sequential cleavage is followed by the gastrulation as the first dynamic event of morphogenesis. Mesodermal induction is the most important event for normal body patterning such as the gastrulation, neural induction and formation of various organs. In the study to search for the mesodermal inducing factor, we reported "activin" as a strong mesoderm-inducible factor by the "animal cap assay", the in vitro assay system using amphibian pluripotential cell mass. We found that activin has mesodemal and endodermal inducing activity in dose-dependent manner, and then established the invitro induction system for various types of tissues and organs including craniofacial cartilage from animal cap cells by the treatments with activin and other inducing factors. Embryonic transplantation method showed that the treatments of animal cap cells for the induction of pronephros, beating heart were able to induce normally functional organs in vitro. These in vitro induction methods are useful for investigation of the molecular mechanisms of organ formation and body patterning in vertebrate development. | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||||||
資源タイプ | conference paper | |||||||||
出版タイプ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
関連情報 | ||||||||||
関連タイプ | isPartOf | |||||||||
識別子タイプ | URI | |||||||||
関連識別子 | http://ir.lib.hiroshima-u.ac.jp/meta-bin/mt-pdetail.cgi?smode=1&edm=0&tlang=1&cd=00014842 | |||||||||
開始ページ | ||||||||||
開始ページ | 95 | |||||||||
書誌情報 |
Hiroshima Conference on Education and Science in Dentistry, 2006 : the 40th Anniversary of Hiroshima University Faculty of Dentistry Hiroshima Conference on Education and Science in Dentistry, 2006 : the 40th Anniversary of Hiroshima University Faculty of Dentistry p. 95-100, 発行日 2006-01-08 |
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旧ID | 101 |