| Item type |
デフォルト(1) |
| 公開日 |
2025-10-14 |
| タイトル |
|
|
タイトル |
Saxitoxin dynamics underlying bloom development and persistence in the bioluminescent HAB species Pyrodinium bahamense |
|
言語 |
en |
| 作成者 |
Cusick, Kathleen D.
Wei, Bofan
Brown, Nicole L.
Widder, Edith A.
Boyer, Gregory L.
|
| 寄与者 |
|
|
寄与者タイプ |
Editor |
|
|
姓名 |
Imai, Ichiro |
|
|
言語 |
en |
| 寄与者 |
|
|
寄与者タイプ |
Editor |
|
|
姓名 |
Matsushima, Ryoji |
|
|
言語 |
en |
| 寄与者 |
|
|
寄与者タイプ |
Editor |
|
|
姓名 |
Nagai, Satoshi |
|
|
言語 |
en |
| 寄与者 |
|
|
寄与者タイプ |
Editor |
|
|
姓名 |
Nishitani, Goh |
|
|
言語 |
en |
| 寄与者 |
|
|
寄与者タイプ |
Editor |
|
|
姓名 |
Sakamoto, Setsuko |
|
|
言語 |
en |
| 寄与者 |
|
|
寄与者タイプ |
Editor |
|
|
姓名 |
Suzuki, Toshiyuki |
|
|
言語 |
en |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
saxitoxin |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Pyrodinium bahamense |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Indian River Lagoon |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
harmful algal bloom |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Pyrodinium bahamense is a saxitoxin (STX)-producing bioluminescent dinoflagellate that blooms in the Indian River Lagoon (IRL), Florida, the bioluminescent bays in Puerto Rico, and the Indo-Pacific. STX is a potent neurotoxin that binds with high affinity to the voltage-gated sodium channel in humans and causes Paralytic Shellfish Poisoning. Its role in the ecology of P. bahamense remains unknown. While P. bahamense previously existed in Florida with no known record of toxicity, toxic blooms have emerged in the IRL over the past 20 years. The core STX biosynthetic pathway genes have been identified. SxtA4 is essential for toxin synthesis and so serves as a molecular proxy for toxicity. Our lab developed a single-cell multiplex PCR assay targeting the 18S rRNA and sxtA4 genes in P. bahamense and found that some cells within the same sub-populations lack sxtA4. In this work, we examine these genotype dynamics in relation to cell abundance and toxicity in spatially and temporally separate populations in the IRL. Our toxin data, normalized as toxin quota per cell, show that toxin content changes substantially both (1) temporally within the same sub-populations and (2) among sub-populations. Assimilating the collective data among sites revealed a significant negative correlation (Spearman Correlation, -0.434; p = 0.02) between toxin quota per cell and cell abundance: toxin quota decreased with increased cell abundance. The potential ecological link between toxicity and bioluminescence is discussed based on these findings. |
|
言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
本文は、ISSHAのHP（ リンク：https://issha.org/publications-resources/conference-proceedings/ ）にて公開。 |
|
言語 |
ja |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
This research and KC’s travel to ICHA was supported by internal funding from UMBC to KC. |
|
言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Ichiro Imai, Ryoji Matsushima, Satoshi Nagai, Goh Nishitani, Setsuko Sakamoto, Toshiyuki Suzuki (Eds.). 2023. Proceedings of the 20th International Conference on Harmful Algae, Hiroshima, Japan. International Society for the Study of Harmful Algae. 【53-56】 pp. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
International Society for the Study of Harmful Algae |
|
言語 |
en |
| 日付 |
|
|
日付 |
2025-10-24 |
|
日付タイプ |
Available |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_5794 |
|
資源タイプ |
conference paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
|
|
ID登録 |
10.15027/0002041265 |
|
ID登録タイプ |
JaLC |
| 書誌情報 |
en : Proceedings of the 20th International Conference on Harmful Algae, Hiroshima, Japan
巻 20,
p. 53-56,
ページ数 4,
発行日 2025-10-24
|
| 見出し |
|
|
大見出し |
Ecology |
|
言語 |
en |
10(pp.53-56).pdf (771 KB)
