{"created":"2025-06-16T05:35:10.187416+00:00","id":2040730,"links":{},"metadata":{"_buckets":{"deposit":"82f07f5b-921e-4dfd-9e3f-4fe2a8c9ec51"},"_deposit":{"created_by":83,"id":"2040730","owner":"83","owners":[83],"pid":{"revision_id":0,"type":"depid","value":"2040730"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02040730","sets":["1730444907710"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Decreased plasma cell-free mitochondrial DNA may be a new biomarker of tachycardia-induced cardiomyopathy in patients with atrial fibrillation","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Miyamoto, Shogo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tokuyama, Takehito","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Okubo, Yousaku","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Okamura, Sho","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Miyauchi, Shunsuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Furutani, Motoki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kobayashi, Yusuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Odake, Yodo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Oguri, Naoto","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Uotani, Yukimi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakashima, Mika","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Akiyama, Rie","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sakai, Takumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ishida, Mari","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakano, Yukiko","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"embargoed access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_f1cf"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"©［ 2024］. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"},{"subitem_rights":"This is not the published version. Please cite only the published version.","subitem_rights_language":"en"},{"subitem_rights":"この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。","subitem_rights_language":"ja"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Tachycardia-induced cardiomyopathy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cell-free mitochondrial DNA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Atrial fibrillation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Biomarker","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Mitophagy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Tachycardia-induced cardiomyopathy (TIC) is a reversible cardiomyopathy caused by tachyarrhythmias, such as atrial fibrillation (AF) tachycardia. The pathogenesis of TIC remains incompletely understood, and there is currently no method to predict its development in patients. In this study, we show that cell-free mitochondrial DNA (mt-cfDNA) levels were significantly lower in the TIC group than in the non-TIC group. Persistent AF, coexisting diabetes mellitus, and decreased mt-cfDNA levels were independently associated with TIC. Decreased mt-cfDNA levels may serve as a novel biomarker for predicting TIC in patients with AF.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"This study was funded by The Japan Society for the Promotion of Science [22K08184], Tokyo, Japan.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_1617186660861":{"attribute_name":"Date","attribute_value_mlt":[{"subitem_date_issued_datetime":"2025-09-19","subitem_date_issued_type":"Available"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186901218":{"attribute_name":"Funding Reference","attribute_value_mlt":[{"subitem_award_numbers":{"subitem_award_number":"22K08184","subitem_award_uri":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22K08184/"},"subitem_award_titles":[{"subitem_award_title":"ゲノム情報を基盤とした非肺動脈起源心房細動の病態解明と至適治療法選択への応用","subitem_award_title_language":"ja"},{"subitem_award_title":"Elucidation of pathophysiology of non-pulmonary artery-derived atrial fibrillation based on genomic information and application to optimal treatment","subitem_award_title_language":"en"}],"subitem_funder_identifiers":{"subitem_funder_identifier_type":"Crossref Funder","subitem_funder_identifier_type_uri":"https://doi.org/10.13039/501100001691"},"subitem_funder_names":[{"subitem_funder_name":"日本学術振興会","subitem_funder_name_language":"ja"},{"subitem_funder_name":"Japan Society for the Promotion of Science","subitem_funder_name_language":"en"}]}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0167-5273","subitem_source_identifier_type":"ISSN"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2024-09-19","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"132579","bibliographicPageStart":"none","bibliographicVolumeNumber":"417","bibliographic_titles":[{"bibliographic_title":"INTERNATIONAL JOURNAL OF CARDIOLOGY","bibliographic_titleLang":"en"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.ijcard.2024.132579","subitem_relation_type_select":"DOI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2025-09-19"}],"fileDate":[{"fileDateType":"Available","fileDateValue":"2025-09-19"}],"filename":"j.ijcard.2024.132579.docx","filesize":[{"value":"60 KB"}],"format":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2040730/files/j.ijcard.2024.132579.docx"},"version_id":"61caf1b7-473a-415b-95b8-37ea0f3d69cb"}]},"item_1732772494514":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"The full-text file will be made open to the public on [19 Sep 2025］ in accordance with publisher's 'Terms and Conditions for Self-Archiving'"}]},"item_title":"Decreased plasma cell-free mitochondrial DNA may be a new biomarker of tachycardia-induced cardiomyopathy in patients with atrial fibrillation","item_type_id":"40036","owner":"83","path":["1730444907710"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-06-18"},"publish_date":"2025-06-18","publish_status":"0","recid":"2040730","relation_version_is_last":true,"title":["Decreased plasma cell-free mitochondrial DNA may be a new biomarker of tachycardia-induced cardiomyopathy in patients with atrial fibrillation"],"weko_creator_id":"83","weko_shared_id":-1},"updated":"2025-06-17T00:47:12.149493+00:00"}