| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2024-03-12 |
| タイトル |
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|
タイトル |
Gradient magnetic-oscillation topography depicts high-frequency oscillations on the brain surface related to the epileptic focus in intractable epilepsy with lesions |
|
言語 |
en |
| 作成者 |
OKAMURA, Akitake
HASHIZUME, Akira
KAGAWA, Kota
KATAGIRI, Masaya
SEYAMA, Go
IIDA, Koji
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
Copyright (c) 2023 Hiroshima University Medical Press |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Epilepsy |
| 主題 |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
High frequency oscillations |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Magnetoencephalography |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Time-frequency analysis |
| 内容記述 |
|
|
内容記述 |
This study aimed to evaluate high-frequency oscillations (HFOs), a potential biomarker of epileptic activity, using magnetoencephalography (MEG). We developed a new spatial filter, termed “gradient magnetic-oscillation topography" (GMOT), to visualize color-coded topographies on the brain surface using a spectrogram calculated at each sensor level. We enrolled 15 patients with lesions and intractable neocortical epilepsy who underwent focal resection surgery and preoperative MEG. We compared GMOT findings with those of the equivalent current dipole (ECD) and resected area based on intracranial video-electroencephalography (IVEEG) or intraoperative electrocorticography (ECoG) with respect to seizure outcomes. We also calculated the proportion of the power of each sensor relative to the entire head at each frequency band. GMOT successfully visualized the high-power gradient magnetic field at the fast ripple band (FR band, 201–330 Hz) and detected the highest power at the FR band around the lesion in 13 of the 15 patients. The resected area included both clustered ECDs and the highest power in the FR band on GMOT in 9 of the 15 patients. The resected area had a statistically higher proportion of power as the frequency band increased in the HFO group (p < 0.01). We visualized high power in the FR band of the brain surface. The areas of highest power in the FR band were correlated with epileptic focus based on IVEEG and intraoperative ECoG. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.24811/hjms.72.1-2_11 |
| 開始ページ |
|
|
開始ページ |
11 |
| 書誌情報 |
en : Hiroshima Journal of Medical Sciences
巻 72,
号 1-2,
p. 11-19,
ページ数 9,
発行日 2023-06
|
| 旧ID |
54944 |
HiroshimaJMedSci_72_11.pdf (14.3 MB)
