| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Basic performance assessment of reagents for measuring soluble FMS-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF) in Japanese women |
|
言語 |
en |
| 作成者 |
NISHIHARA, Haruna
YAMAZAKI, Shinichi
ARASE, Takashi
YAMAZAKI, Tomomi
KUDO, Yoshiki
YOKOZAKI, Michiya
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2022 Hiroshima University Medical Press |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
sFlt-1 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
PlGF |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
hypertensive disorders of pregnancy |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
preeclampsia |
| 内容記述 |
|
|
内容記述 |
Among the factors associated with angiogenesis, soluble FMS-like tyrosine kinase-1 (sFlt-1) is antiangiogenic and placental growth factor (PlGF) is proangiogenic. The sFlt-1/PlGF ratio is considered useful for the short-term prediction of preeclampsia (PE) in high-risk pregnancies and has been used clinically in Japan since July 2021. Regarding the clinical use of the sFlt-1/PlGF ratio in Japan, there have been no published reports demonstrating that sFlt-1 and PlGF assay reagents have the same basic performance in Japanese and European women. To our knowledge, we conducted the first basic performance assessment of the sFlt-1 and PlGF assay reagents using sera from Japanese women. We obtained satisfactory results for repeatability, intermediate precision, linearity, effects of interferents, and the LoQ. The sFlt-1 and PlGF assay reagents performed well, and we believe that they are entirely adequate for use in routine clinical assays of Japanese patients, similar to those in European patients. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2433-7668 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
51 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 71,
号 3-4,
p. 51-55,
発行日 2022-12
|
| 旧ID |
53497 |
HiroshimaJMedSci_71_51.pdf (290.2 KB)
