| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
The Correlation between Serum Vascular Endothelial Growth Factor (VEGF) Levels and Size of Colorectal Cancer Tumors |
|
言語 |
en |
| 作成者 |
Pangarsa, Eko A
Suharti, C
Santosa, D
Setiawan, Budi
Ulthofiah, Aniq
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2018 Hiroshima University Medical Press |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Angiogenesis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Colorectal Cancer |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Tumor size |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
VEGF |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Background: Angiogenesis plays an important role in progression of colorectal carcinoma (CRC). Vascular endothelial growth factor (VEGF) is the predominant angiogenic factor in CRC and plays important role in cell mitosis, change in cell shape and increases vascular permeability. Vascular endothelial growth factor is expressed in approximately 50% of CRCs, and considered an important angiogenic factor in growth and development of CRC. In this study, we examined VEGF serum levels to asses corelation between serum VEGF levels and size of CRC tumors. Patients and Methods: This cross sectional study involved 17 CRC patients with stage I, II, III. who had undergone large bowel resection at Karyadi Hospital and had not chemotherapy. Size of tumors grading system according to TNM system based on abdominal CT, whether serum levels of VEGF was assessed by ELISA. Results: In this study, we found the grading tumor size T1, T2 and T3 was 23,5%, 29,4 % and 47,1 % respectively. Significant statistical correlation (p=0.001) was found between serum VEGF levels and size tumors of CRC with strong relationship (rho>0,7). Conclusion: This study showed a correlation between serum VEGF levels and size of colorectal cancer tumors. Whether VEGF levels is affected by surgical procedure, we need further study to evaluate serum VEGF levels before surgical and tumor size according to treatment response. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
97 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 67,
p. 97-100,
発行日 2018-05
|
| 旧ID |
45850 |
HiroshimaJMedSci_67s_97.pdf (186.4 KB)
