{"created":"2025-02-23T06:36:52.711939+00:00","id":2013561,"links":{},"metadata":{"_buckets":{"deposit":"ad2c37d2-51d7-46f2-94ed-3d9dae1dc6dc"},"_deposit":{"created_by":41,"id":"2013561","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2013561"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02013561","sets":["1727147343679:1730442224523:1730442272519"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Clinical Evaluation of Low-dose Cisplatin and 5-Fluorouracil as Adjuvant Chemoradiotherapy for Advanced Squamous Cell Carcinoma of the Esophagus","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimizu, Katsuhiko","creatorNameLang":"en"}],"familyNames":[{"familyName":"Shimizu","familyNameLang":"en"}],"givenNames":[{"givenName":"Katsuhiko","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hihara, Jun","creatorNameLang":"en"}],"familyNames":[{"familyName":"Hihara","familyNameLang":"en"}],"givenNames":[{"givenName":"Jun","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yoshida, Kazuhiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Yoshida","familyNameLang":"en"}],"givenNames":[{"givenName":"Kazuhiro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Toge, Tetsuya","creatorNameLang":"en"}],"familyNames":[{"familyName":"Toge","familyNameLang":"en"}],"givenNames":[{"givenName":"Tetsuya","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"Hiroshima University Medical Press"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Adjuvant therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Adjuvant chemoradiotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Low-dose cisplatin and 5-fluorouracil","subitem_subject_scheme":"Other"},{"subitem_subject":"Advanced esophageal cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"The aim of this retrospective study was to evaluate the effectiveness of low-dose cisplatin and 5-fluorouracil (low-dose FP) as an adjuvant chemoradiotherapy for resected advanced squamous cell carcinoma of the esophagus. From 1994 to 1999, 57 patients who showed an invasion of the tumor over the muscularis propria (T2-T4), regional lymph node metastasis (Nl), and no distant metastasis (MO) were enrolled in this analysis. Postoperative chemoradiotherapy (CRT group) was performed on 14 of the patients, and they were compared to the patients who underwent surgery alone (S group) using the matched pair algorithm. In the CRT group, chemotherapy of low-dose FP was combined with concurrent radiotherapy after the esophagectomy. A side-effect of severe dysphagia (NCI-CTC Grade 3) was observed in 4 patients (28.6%) and leukocytopenia in 1 patient (7.1%) among the CRT group. The overall survival rate of the CRT group and matched S group were 35. 7% and 28.5% at 5 years, respectively, with no significant difference. In the CRT group, 7 of 14 patients (50%) had a recurrence. The recurrence rate was slightly lower than in the S group (57%), with no significant difference. This combined chemoradiotherapy using low-dose FP did not improve the prognosis of patients with resected advanced esophageal carcinoma.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University Medical Press"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"67"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"71","bibliographicPageStart":"67","bibliographicVolumeNumber":"54","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_54_67.pdf","filesize":[{"value":"409.3 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2013561/files/HiroshimaJMedSci_54_67.pdf"},"version_id":"566287e3-60f1-4ac9-bf4c-31700fdd2864"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"37662"},"item_title":"Clinical Evaluation of Low-dose Cisplatin and 5-Fluorouracil as Adjuvant Chemoradiotherapy for Advanced Squamous Cell Carcinoma of the Esophagus","item_type_id":"40003","owner":"41","path":["1730442272519"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2013561","relation_version_is_last":true,"title":["Clinical Evaluation of Low-dose Cisplatin and 5-Fluorouracil as Adjuvant Chemoradiotherapy for Advanced Squamous Cell Carcinoma of the Esophagus"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T03:19:46.744151+00:00"}