{"created":"2025-02-23T06:31:31.239384+00:00","id":2013375,"links":{},"metadata":{"_buckets":{"deposit":"5e4959f5-4c8d-473d-be91-fdf2fce7d128"},"_deposit":{"created_by":41,"id":"2013375","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2013375"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02013375","sets":["1727147343679:1730442224523:1730442308496"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Clinical Evaluation of Human Granulocyte Colony-stimulating Factor in Chemotherapy for Ovarian Cancer","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nagai, Nobutaka","creatorNameLang":"en"}],"familyNames":[{"familyName":"Nagai","familyNameLang":"en"}],"givenNames":[{"givenName":"Nobutaka","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takehara, Kazuhiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Takehara","familyNameLang":"en"}],"givenNames":[{"givenName":"Kazuhiro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Murakami, Takahiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Murakami","familyNameLang":"en"}],"givenNames":[{"givenName":"Takahiro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ohama, Koso ","creatorNameLang":"en"}],"familyNames":[{"familyName":"Ohama","familyNameLang":"en"}],"givenNames":[{"givenName":"Koso ","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Miyaoka, Shigeki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Miyaoka","familyNameLang":"en"}],"givenNames":[{"givenName":"Shigeki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Fujii, Tsuneo","creatorNameLang":"en"}],"familyNames":[{"familyName":"Fujii","familyNameLang":"en"}],"givenNames":[{"givenName":"Tsuneo","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Matsubayashi, Shigeru","creatorNameLang":"en"}],"familyNames":[{"familyName":"Matsubayashi","familyNameLang":"en"}],"givenNames":[{"givenName":"Shigeru","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"G-CSF","subitem_subject_scheme":"Other"},{"subitem_subject":"Ovarian cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"The clinical evaluation of human granulocyte colony-stimulating factor (G-CSF) in 38 patients treated with chemotherapy for ovarian cancer stage III was investigated among 3 groups. G-CSF was not given in group A (19 courses), was administered from day 5 of chemotherapy in group B (53 courses), and was given when the WBC count decreased to below 2,000/mm3 in group C (29 courses).　　    The time to nadir was significantly shorter in group B compared with groups A and C and revealed 10 days for the WBC count and 11 days for the neutrophil count (p<0.01), with mean nadir values of 2,896/mm3 and 982/mm3 respectively, and so the count of WBC and neutrophil have been kept during the course. The effect of G-CSF was not modified by age, body weight or the number of chemotherapy courses in groups B and C. These results demonstrate that early treatment with G-CSF may allow increased intensity of chemotherapy by using greater doses or by shortening of the interval between cycles.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University Medical Press"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"99"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"103","bibliographicPageStart":"99","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_44_99.pdf","filesize":[{"value":"447.9 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2013375/files/HiroshimaJMedSci_44_99.pdf"},"version_id":"ed2f6078-dc51-40e1-841c-0db21708ef30"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"37868"},"item_title":"Clinical Evaluation of Human Granulocyte Colony-stimulating Factor in Chemotherapy for Ovarian Cancer","item_type_id":"40003","owner":"41","path":["1730442308496"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2013375","relation_version_is_last":true,"title":["Clinical Evaluation of Human Granulocyte Colony-stimulating Factor in Chemotherapy for Ovarian Cancer"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T03:07:34.508279+00:00"}