{"created":"2025-02-23T06:31:15.938770+00:00","id":2013366,"links":{},"metadata":{"_buckets":{"deposit":"555ccf4c-1813-42da-a8b5-986c1ed19a5b"},"_deposit":{"created_by":41,"id":"2013366","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2013366"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02013366","sets":["1727147343679:1730442224523:1730442311859"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Mac-1 Expression and Superoxide Generation of the Peripheral Polymorphonuclear Leukocyte following Gastrectomy and Esophagectomy","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Imamura, Yuji","creatorNameLang":"en"}],"familyNames":[{"familyName":"Imamura","familyNameLang":"en"}],"givenNames":[{"givenName":"Yuji","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yokoyama, Takashi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Yokoyama","familyNameLang":"en"}],"givenNames":[{"givenName":"Takashi","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Murakami, Yoshiaki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Murakami","familyNameLang":"en"}],"givenNames":[{"givenName":"Yoshiaki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hiyama, Eiso","creatorNameLang":"en"}],"familyNames":[{"familyName":"Hiyama","familyNameLang":"en"}],"givenNames":[{"givenName":"Eiso","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takesue, Yoshio","creatorNameLang":"en"}],"familyNames":[{"familyName":"Takesue","familyNameLang":"en"}],"givenNames":[{"givenName":"Yoshio","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kodama, Takashi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Kodama","familyNameLang":"en"}],"givenNames":[{"givenName":"Takashi","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Matsuura, Yuichiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Matsuura","familyNameLang":"en"}],"givenNames":[{"givenName":"Yuichiro","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"PMN","subitem_subject_scheme":"Other"},{"subitem_subject":"Mac-1","subitem_subject_scheme":"Other"},{"subitem_subject":"G-CSF","subitem_subject_scheme":"Other"},{"subitem_subject":"Superoxide","subitem_subject_scheme":"Other"},{"subitem_subject":"Esophagectomy","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"The aim of this study was to evaluate the characteristics of the polymorphonuclear leukocyte (PMN) function after surgical stress. We investigated Mac-1 expression and superoxide generation by peripheral PMNs and serum granulocyte-colony stimulating factor (G-CSF) concentrations in 15 patients who underwent either gastrectomy (n=8) or esophagectomy (n=7). The serum G-CSF rapidly increased within 24 hours after operation. The maximum levels of serum G-CSF in the cases of esophagectomy were about 5-8 fold those of gastrectomy, although the increases in PMN counts within 24 hours of esophagectomy were lower than those after gastrectomy. Mac-1 expression and superoxide generation by PMN s after gastrectomy increased significantly, in parallel with increases in the PMN counts and serum G-CSF. After esophagectomy, Mac-1 expression on peripheral PMN s remained elevated through the 7th day after operation, while superoxide generation by PMN s in response to PMA declined to below preoperative levels after the 3rd day. These results suggest that, after major surgery such as esophagectomy, there is a discrepancy between Mac-1 expression and superoxide generation by the peripheral PMN despite a high level of serum G-CSF.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University Medical Press"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"39"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"46","bibliographicPageStart":"39","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_44_39.pdf","filesize":[{"value":"696.8 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2013366/files/HiroshimaJMedSci_44_39.pdf"},"version_id":"5efcd1f0-990c-44a1-9722-345722e01cb7"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"37859"},"item_title":"Mac-1 Expression and Superoxide Generation of the Peripheral Polymorphonuclear Leukocyte following Gastrectomy and Esophagectomy","item_type_id":"40003","owner":"41","path":["1730442311859"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2013366","relation_version_is_last":true,"title":["Mac-1 Expression and Superoxide Generation of the Peripheral Polymorphonuclear Leukocyte following Gastrectomy and Esophagectomy"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T03:07:00.420085+00:00"}