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BCR-ABL mRNA Expression in Patients with Chronic Myeloproliferative Disorders : Absence of BCR-ABL Fused Clone except Chronic Myelocytic Leukemia
https://hiroshima.repo.nii.ac.jp/records/2013320
https://hiroshima.repo.nii.ac.jp/records/2013320e7b0784d-0754-4172-8c64-0b1cc3cf3143
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_42_67.pdf (561.6 KB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||
| タイトル | ||||||||
| タイトル | BCR-ABL mRNA Expression in Patients with Chronic Myeloproliferative Disorders : Absence of BCR-ABL Fused Clone except Chronic Myelocytic Leukemia | |||||||
| 言語 | en | |||||||
| 作成者 |
Nakata, Yoshio
× Nakata, Yoshio
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| アクセス権 | ||||||||
| アクセス権 | open access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Breakpoint cluster region | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | c-Abl | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Chronic myeloproliferative disorders | |||||||
| 主題 | ||||||||
| 主題Scheme | NDC | |||||||
| 主題 | 490 | |||||||
| 内容記述 | ||||||||
| 内容記述 | Bcr-abl mRNA expression was studied in patients with chronic myeloproliferative disorders (CMPD) by the reverse transcriptase-polymerase chain reaction (RT-PCR) method. A bcr-abl transcript was not found in any patient with polycythemia vera, essential thrombocythemia or primary myelofibrosis, suggesting that the bcr-abl rearranged clone is not present in CMPD other than chronic myelogenous leukemia (CML). In CML clinical and laboratory data were compared from three bcr-abl types: the bcr exon 2-abl exon 2 (B2-A2) type, bcr exon 3-abl exon 2 (B3-A2) type and the co-expression type. Age at diagnosis tended to be younger (p=0.08) in the co-expression type, and the platelet count tended to be lower (p=0.11) in the B2-A2 type. However, there was no difference in other data, including the duration of the chronic phase and the phenotype of blasts at blast crisis. | |||||||
| 言語 | en | |||||||
| 出版者 | ||||||||
| 出版者 | Hiroshima University Medical Press | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0018-2052 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00664312 | |||||||
| 開始ページ | ||||||||
| 開始ページ | 67 | |||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 42, 号 2, p. 67-71, 発行日 1993-06 |
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| 旧ID | 37917 | |||||||
