{"created":"2025-02-23T06:29:11.223360+00:00","id":2013294,"links":{},"metadata":{"_buckets":{"deposit":"c7479c9c-28cd-49f9-8135-21983dc45f57"},"_deposit":{"created_by":41,"id":"2013294","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2013294"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02013294","sets":["1727147343679:1730442224523:1730442320483"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Susceptibility of Methicillin-resistant Staphylococcus aureus Clinical Isolates to Various Antimicrobial Agents","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sowa, Sho-ichiro ","creatorNameLang":"en"}],"familyNames":[{"familyName":"Sowa","familyNameLang":"en"}],"givenNames":[{"givenName":"Sho-ichiro ","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Masumi, Noriko","creatorNameLang":"en"}],"familyNames":[{"familyName":"Masumi","familyNameLang":"en"}],"givenNames":[{"givenName":"Noriko","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Inouye, Yoshio","creatorNameLang":"en"}],"familyNames":[{"familyName":"Inouye","familyNameLang":"en"}],"givenNames":[{"givenName":"Yoshio","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakamura, Shoshiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Nakamura","familyNameLang":"en"}],"givenNames":[{"givenName":"Shoshiro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takesue, Yoshio","creatorNameLang":"en"}],"familyNames":[{"familyName":"Takesue","familyNameLang":"en"}],"givenNames":[{"givenName":"Yoshio","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yokoyama, Takashi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Yokoyama","familyNameLang":"en"}],"givenNames":[{"givenName":"Takashi","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Methicillin-resistant Staphylococcus aureus (MRSA)","subitem_subject_scheme":"Other"},{"subitem_subject":"Antibiotic resistance","subitem_subject_scheme":"Other"},{"subitem_subject":"Vancomycin","subitem_subject_scheme":"Other"},{"subitem_subject":"Arbekacin","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Resistance patterns against 23 antimicrobial agents were examined for 42 strains of methicillin-resistant Staphylococcus aureus (MRSA). Thirty-four strains were isolated at Hiroshima University Hospital during 1984-1990 and 8 strains were collected in Tokushima city in 1986. Overall resistance to the antimicrobial agents in clinical use is summarized as follows: methicillin 100%, flomoxef 93% (β-lactams); kanamycin 98%, tobramycin 88%, amikacin 83%, isepamicin 81 %, gentamicin 60%, dibekacin 64%, arbekacin 0% (aminocyclitol aminoglycosides); ofloxacin 31 %, TA-167 33% (fluoroquinolones); erythromycin 100%, clarithromycin 100%, josamycin 71 % (macrolides); vancomycin 0% (glycopeptide); tetracycline 43%, minocycline 31 % (tetracyclines); fosfomycin 93%. The MRSA strains remained susceptible to the non-clinical peptide group of antibiotics except for mikamycin B: mikamycin A 2%, mikamycin B 69%, nosiheptide 0%, bottromycin A2 0%, bottromycin D-1 0%, bottromycin D-2 0%.　　    Since April 1990, the MRSA strains isolated at Hiroshima University Hospital showed a tendency to acquire resistance to tetracyclines and fluoroquinolones and to lose mikamycin B-resistance.　　    As of August 1990, none of the MRSA strains isolated at Hiroshima University Hospital was resistant to vancomycin and arbekacin.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University Medical Press"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"137"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"144","bibliographicPageStart":"137","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"1797744","subitem_relation_type_select":"PMID"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_40_137.pdf","filesize":[{"value":"728.2 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2013294/files/HiroshimaJMedSci_40_137.pdf"},"version_id":"1db94078-d631-4234-b69b-a1e02894aeb9"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"38027"},"item_title":"Susceptibility of Methicillin-resistant Staphylococcus aureus Clinical Isolates to Various Antimicrobial Agents","item_type_id":"40003","owner":"41","path":["1730442320483"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2013294","relation_version_is_last":true,"title":["Susceptibility of Methicillin-resistant Staphylococcus aureus Clinical Isolates to Various Antimicrobial Agents"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T03:02:49.175920+00:00"}