| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
The Effects of Fenitrothion Emulsion (Organic Phosphorous Pesticide) and Its Degraded Solution on Mice |
|
言語 |
en |
| 作成者 |
Hiraoka, Yukio
Imada, Atsushi
Tanaka, Junko
Okuda, Hisanori
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Degraded and undegrnded fenitrothion emulsion |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Mouse |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Embryo |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Toxicity |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Experiments were carried out to examine the effects of degradation products on mice. Fenitrothion (MEP) emulsion, a kind of an organic phosphorous insecticide, adjusted to pH 8, pH 10, and pH 14 were degraded by exposure to natural sunlight. Physiological saline, an untreated MEP emulsion, and the three degraded solutions were prepared as experimental chemicals and were administered subcutaneously at a dosage of 0.1 ml/10 g body weight (BW) into the backs of pregnant mice once a day, from the 3rd to the 15th fetal day. Each dose included 20, 40, or 90 mg/kgBW of MEP and several degradation products of MEP. LD50 was determined according to Behrens' method. The mean fetal body weights of 18th day of pregnancy in 40 and 90 mg/kgBW of MEP of the pH 8 degraded solution were 1.09 and 1.16 g, respectively, significantly lower than that of untreated MEP emulsion (1.27 g). Further, LD50 values of the three kinds of degraded solutions were 60-120 mg/kgBW, much lower than that of the untreated MEP emulsion (410 mg/kgBW). These results indicate that the degradation products of MEP emulsion degraded by the exposure of sunlight have an influence on both adult and fetal mice. |
|
言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
This study was supported by a Grant-in-Aid for General Scientific Research from the Ministry of Education, Science, and Culture. |
| 出版者 |
|
|
出版者 |
Hiroshima University Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
2637249 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
209 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 38,
号 4,
p. 209-212,
発行日 1989-12
|
| 旧ID |
38132 |
HiroshimaJMedSci_38_209.pdf (212.5 KB)
