{"created":"2025-02-23T06:25:39.690174+00:00","id":2013175,"links":{},"metadata":{"_buckets":{"deposit":"82fdd8ea-b539-4cb3-8212-cf5d99b9ba84"},"_deposit":{"created_by":41,"id":"2013175","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2013175"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02013175","sets":["1727147343679:1730442224523:1730442329532"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Immunohistochemical Analysis of Colorectal Cancer among Atomic Bomb Survivors in Hiroshima","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"YAMAMOTO, Masami","creatorNameLang":"en"}],"familyNames":[{"familyName":"YAMAMOTO","familyNameLang":"en"}],"givenNames":[{"givenName":"Masami","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"YAMAMOTO, Tetsuro","creatorNameLang":"en"}],"familyNames":[{"familyName":"YAMAMOTO","familyNameLang":"en"}],"givenNames":[{"givenName":"Tetsuro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"HATA, Jotaro","creatorNameLang":"en"}],"familyNames":[{"familyName":"HATA","familyNameLang":"en"}],"givenNames":[{"givenName":"Jotaro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"NAKAGAWA, Hitoshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"NAKAGAWA","familyNameLang":"en"}],"givenNames":[{"givenName":"Hitoshi","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"NAKATSUKA, Hirofumi","creatorNameLang":"en"}],"familyNames":[{"familyName":"NAKATSUKA","familyNameLang":"en"}],"givenNames":[{"givenName":"Hirofumi","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"TAHARA, Eiichi","creatorNameLang":"en"}],"familyNames":[{"familyName":"TAHARA","familyNameLang":"en"}],"givenNames":[{"givenName":"Eiichi","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Colorectal cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Atomic bomb survivors","subitem_subject_scheme":"Other"},{"subitem_subject":"Immunohistochemistry","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"In order to elucidate the biological characteristics of colorectal cancer among atomic bomb survivors in Hiroshima, a total of 159 cases of colorectal cancers comprising 73 cases in exposed atomic bomb survivors and 86 cases in non-exposed individuals were examined histologically and immunohistochemically for various functioning proteins. No statistical differences could be demonstrated in the incidence of various marker expressions of colorectal cancers between the exposed group and control group. However, comparison by the site of colorectal cancer showed that sigmoid colon cancers in the exposed group or high dose group showed a significantly higher frequency of glycoproteins such as α1-antichymotrypsin (ACT), secretory component (SC), α1-antitrypsin (AAT), and human chorionic gonadotropin (HCG) when compared with the control group. These results correlated well with the epidemiological data that the radiation effect on the incidence of colorectal cancer in atomic bomb survivors was most remarkable in the sigmoid colon.","subitem_description_language":"en"},{"subitem_description":"This study was supported in part by Grants in Aid for Cancer Research from the Ministry of Education, Science and Culture, Japan.","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University Medical Press"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"387"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1987-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"393","bibliographicPageStart":"387","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"3448061","subitem_relation_type_select":"PMID"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_36_387.pdf","filesize":[{"value":"3.6 MB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2013175/files/HiroshimaJMedSci_36_387.pdf"},"version_id":"46e4c88d-c578-429a-9475-8da9bc226a66"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"50006"},"item_title":"Immunohistochemical Analysis of Colorectal Cancer among Atomic Bomb Survivors in Hiroshima","item_type_id":"40003","owner":"41","path":["1730442329532"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2013175","relation_version_is_last":true,"title":["Immunohistochemical Analysis of Colorectal Cancer among Atomic Bomb Survivors in Hiroshima"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-02-26T04:47:35.640894+00:00"}